Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins

Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane sk...

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Bibliographic Details
Main Authors: Jamilly Kelly Oliveira Neves, José Alexsandro da Silva, Paula Cristina Souza Barbosa, Fabiano de Sousa Vargas, Lidiam Maia Leandro, Valdir Florêncio da Veiga-Junior
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/4/3866/
Description
Summary:Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane skeletons) are different for each Copaifera species and have been linked to several reported biological activities, ranging from anti-tumoral to embriotoxic effects. This review presents all the substances already described in this oleoresin, together with structures and activities of its main terpenoids.
ISSN:1420-3049