Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites
Natural products are a vital source for agriculture, medicine, cosmetic and other fields. Among them alkylamides are a broad and expanding group found in at least 33 plant families. Frequently, they possess a simple carbon skeleton architecture but show broad structural variability and important pro...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/11/12/1765 |
| _version_ | 1797506443982667776 |
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| author | Antonio Evidente Marco Masi |
| author_facet | Antonio Evidente Marco Masi |
| author_sort | Antonio Evidente |
| collection | DOAJ |
| description | Natural products are a vital source for agriculture, medicine, cosmetic and other fields. Among them alkylamides are a broad and expanding group found in at least 33 plant families. Frequently, they possess a simple carbon skeleton architecture but show broad structural variability and important properties such as immunomodulatory, antimicrobial, antiviral, larvicidal, insecticidal and antioxidant properties, amongst others. Despite to these several and promising biological activities, up to today, only two reviews have been published on natural alkylamides. One focuses on their potential pharmacology application and their distribution in the plant kingdom and the other one on the bioactive alkylamides specifically found in <i>Annona</i> spp. The present review is focused on the plant bioactive cinnamoyltyramine alkylamides, which are subject of several works reported in the literature. Furthermore, the co-metabolites isolated from the same natural sources and their biological activities are also reported. |
| first_indexed | 2024-03-10T04:33:40Z |
| format | Article |
| id | doaj.art-5f00a464db8e4b7f98c24f68f8cae584 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T04:33:40Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-5f00a464db8e4b7f98c24f68f8cae5842023-11-23T03:58:48ZengMDPI AGBiomolecules2218-273X2021-11-011112176510.3390/biom11121765Natural Bioactive Cinnamoyltyramine Alkylamides and Co-MetabolitesAntonio Evidente0Marco Masi1Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant’Angelo, Via Cintia 4, 80126 Naples, ItalyDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant’Angelo, Via Cintia 4, 80126 Naples, ItalyNatural products are a vital source for agriculture, medicine, cosmetic and other fields. Among them alkylamides are a broad and expanding group found in at least 33 plant families. Frequently, they possess a simple carbon skeleton architecture but show broad structural variability and important properties such as immunomodulatory, antimicrobial, antiviral, larvicidal, insecticidal and antioxidant properties, amongst others. Despite to these several and promising biological activities, up to today, only two reviews have been published on natural alkylamides. One focuses on their potential pharmacology application and their distribution in the plant kingdom and the other one on the bioactive alkylamides specifically found in <i>Annona</i> spp. The present review is focused on the plant bioactive cinnamoyltyramine alkylamides, which are subject of several works reported in the literature. Furthermore, the co-metabolites isolated from the same natural sources and their biological activities are also reported.https://www.mdpi.com/2218-273X/11/12/1765alkylamidecinnamoyltyramineplant sourcesdifferent carbon skeletonbiological activity |
| spellingShingle | Antonio Evidente Marco Masi Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites Biomolecules alkylamide cinnamoyltyramine plant sources different carbon skeleton biological activity |
| title | Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites |
| title_full | Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites |
| title_fullStr | Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites |
| title_full_unstemmed | Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites |
| title_short | Natural Bioactive Cinnamoyltyramine Alkylamides and Co-Metabolites |
| title_sort | natural bioactive cinnamoyltyramine alkylamides and co metabolites |
| topic | alkylamide cinnamoyltyramine plant sources different carbon skeleton biological activity |
| url | https://www.mdpi.com/2218-273X/11/12/1765 |
| work_keys_str_mv | AT antonioevidente naturalbioactivecinnamoyltyraminealkylamidesandcometabolites AT marcomasi naturalbioactivecinnamoyltyraminealkylamidesandcometabolites |