Antibody-Mediated Delivery of VEGF-C Promotes Long-Lasting Lymphatic Expansion That Reduces Recurrent Inflammation

Antibody-Mediated Delivery of VEGF-C Promotes Long-Lasting Lymphatic Expansion That Reduces Recurrent Inflammation

The lymphatic vascular system plays a fundamental role in inflammation by draining interstitial fluid, immune cells, antigens, and inflammatory mediators from peripheral tissues. Site-specific delivery of the lymphangiogenic growth factor VEGF-C alleviates acute inflammation in mouse models of psori...

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Bibliographic Details
Main Authors: Nikola Cousin, Sophie Bartel, Jeannette Scholl, Carlotta Tacconi, Annina Egger, Gudrun Thorhallsdottir, Dario Neri, Lothar C. Dieterich, Michael Detmar
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
lymphatic vessel
VEGF-C
targeted delivery
dermatitis
psoriasis
recurrence
Online Access:https://www.mdpi.com/2073-4409/12/1/172

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