Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods

In recent times, there has been a concerning and noteworthy rise in the global use of sodium nitrite for suicidal purposes. This is facilitated either through the employment of specialized “suicide kits” or by acquiring sodium nitrite through alternative means. Additionally, another occurrence contr...

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Main Authors: Kaja Tusiewicz, Patryk Kuropka, Elżbieta Workiewicz, Olga Wachełko, Paweł Szpot, Marcin Zawadzki
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/11/10/832
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author Kaja Tusiewicz
Patryk Kuropka
Elżbieta Workiewicz
Olga Wachełko
Paweł Szpot
Marcin Zawadzki
author_facet Kaja Tusiewicz
Patryk Kuropka
Elżbieta Workiewicz
Olga Wachełko
Paweł Szpot
Marcin Zawadzki
author_sort Kaja Tusiewicz
collection DOAJ
description In recent times, there has been a concerning and noteworthy rise in the global use of sodium nitrite for suicidal purposes. This is facilitated either through the employment of specialized “suicide kits” or by acquiring sodium nitrite through alternative means. Additionally, another occurrence contributing to nitrite poisoning is the recreational utilization of nitrites in the form of volatile aliphatic esters of nitrous acid, commonly referred to as “poppers”. Based on current available papers and reports on the subject of nitrates, nitrites, and poppers intoxications, an epidemiological analysis and evaluation of analytical methods were performed. A total of 128 papers, documenting a collective count of 492 intoxication cases, were identified. Additionally, in order to complete the epidemiological profile of nitrite poisoning, the authors briefly examined six cases of nitrite intoxication that were under investigation in our laboratory. Furthermore, a review of nitrite poisoning cases over the past 100 years shows that the old poison is still in use and poses a substantial risk to society.
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spelling doaj.art-5f0b05c5ca04446cbcd9ea253615fa3e2023-11-19T18:21:38ZengMDPI AGToxics2305-63042023-10-01111083210.3390/toxics11100832Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical MethodsKaja Tusiewicz0Patryk Kuropka1Elżbieta Workiewicz2Olga Wachełko3Paweł Szpot4Marcin Zawadzki5Department of Forensic Medicine, Wroclaw Medical University, 4 J. Mikulicza-Radeckiego Street, 50345 Wroclaw, PolandInstitute of Toxicology Research, 45 Kasztanowa Street, 55093 Borowa, PolandInstitute of Toxicology Research, 45 Kasztanowa Street, 55093 Borowa, PolandInstitute of Toxicology Research, 45 Kasztanowa Street, 55093 Borowa, PolandDepartment of Forensic Medicine, Wroclaw Medical University, 4 J. Mikulicza-Radeckiego Street, 50345 Wroclaw, PolandFaculty of Medicine, Wroclaw University of Science and Technology, 27 Wybrzeże Wyspiańskiego Street, 50370 Wroclaw, PolandIn recent times, there has been a concerning and noteworthy rise in the global use of sodium nitrite for suicidal purposes. This is facilitated either through the employment of specialized “suicide kits” or by acquiring sodium nitrite through alternative means. Additionally, another occurrence contributing to nitrite poisoning is the recreational utilization of nitrites in the form of volatile aliphatic esters of nitrous acid, commonly referred to as “poppers”. Based on current available papers and reports on the subject of nitrates, nitrites, and poppers intoxications, an epidemiological analysis and evaluation of analytical methods were performed. A total of 128 papers, documenting a collective count of 492 intoxication cases, were identified. Additionally, in order to complete the epidemiological profile of nitrite poisoning, the authors briefly examined six cases of nitrite intoxication that were under investigation in our laboratory. Furthermore, a review of nitrite poisoning cases over the past 100 years shows that the old poison is still in use and poses a substantial risk to society.https://www.mdpi.com/2305-6304/11/10/832nitrates intoxicationnitrites intoxicationepidemiologyold poisonsnitrates detection
spellingShingle Kaja Tusiewicz
Patryk Kuropka
Elżbieta Workiewicz
Olga Wachełko
Paweł Szpot
Marcin Zawadzki
Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods
Toxics
nitrates intoxication
nitrites intoxication
epidemiology
old poisons
nitrates detection
title Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods
title_full Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods
title_fullStr Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods
title_full_unstemmed Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods
title_short Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods
title_sort nitrites an old poison or a current hazard epidemiology of intoxications covering the last 100 years and evaluation of analytical methods
topic nitrates intoxication
nitrites intoxication
epidemiology
old poisons
nitrates detection
url https://www.mdpi.com/2305-6304/11/10/832
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