Trichosanthin Promotes Anti-Tumor Immunity through Mediating Chemokines and Granzyme B Secretion in Hepatocellular Carcinoma

Trichosanthin Promotes Anti-Tumor Immunity through Mediating Chemokines and Granzyme B Secretion in Hepatocellular Carcinoma

Trichosanthin (TCS) is a type I ribosome-inactivating protein extracted from the tuberous root of the plant <i>Trichosanthes</i>. TCS shows promising potential in clinical drug abortion, anti-tumor and immunological regulation. However, the molecular mechanisms of its anti-tumor and immu...

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Bibliographic Details
Main Authors: Kaifang Wang, Xiaona Wang, Minghuan Zhang, Zhenguang Ying, Zeyao Zhu, Kin Yip Tam, Chunman Li, Guowei Zhou, Feng Gao, Meiqi Zeng, Stephen Cho Wing Sze, Xia Wang, Ou Sha
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Trichosanthin (TCS)
hepatocellular carcinoma (HCC)
T cell
chemokine
Granzyme B (GrzB)
apoptosis
Online Access:https://www.mdpi.com/1422-0067/24/2/1416

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https://www.mdpi.com/1422-0067/24/2/1416

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