The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mm

Abstract We aimed to investigate the ability of the C-reactive protein-to-albumin ratio (CAR) to predict ascending aorta progression in patients with 40–50 mm diameter of ascending aortic dilatation. A total of 182 diagnosed patients with ascending aortic diameters of 40–50 mm were enrolled in this...

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Main Authors: Ahmet Dolapoglu, Eyüp Avci, Tuncay Kiris
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-022-02003-5
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author Ahmet Dolapoglu
Eyüp Avci
Tuncay Kiris
author_facet Ahmet Dolapoglu
Eyüp Avci
Tuncay Kiris
author_sort Ahmet Dolapoglu
collection DOAJ
description Abstract We aimed to investigate the ability of the C-reactive protein-to-albumin ratio (CAR) to predict ascending aorta progression in patients with 40–50 mm diameter of ascending aortic dilatation. A total of 182 diagnosed patients with ascending aortic diameters of 40–50 mm were enrolled in this study. The study population was divided into tertiles based on yearly ascending aortic growth rate values. Group I (n = 137) was defined as a value in the lower 2 tertiles (ascending aorta growth ≤ 1.00 mm/year), and group II (n = 45) was defined as a value in the third tertile (ascending aorta growth > 1.00 mm/year). Hypertension, chronic obstructive pulmonary disease, positive family history, and CAR were found to be independent risk factors for ascending aorta growth > 1.00 mm/year. The area under the ROC curve (AUC) of CAR was 0.771(95% CI 0.689–0.854) for predicting ascending aorta growth > 1.00 mm/year. In patients with 40–50 mm ascending aneurysms, CAR may be useful to predict ascending aorta progression.
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spelling doaj.art-5f10c6231a02460688fc55160c1064572022-12-22T04:30:03ZengBMCJournal of Cardiothoracic Surgery1749-80902022-10-011711710.1186/s13019-022-02003-5The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mmAhmet Dolapoglu0Eyüp Avci1Tuncay Kiris2Department of Cardiovascular Surgery, Balikesir University Medical FacultyDepartment of Cardiology, Balikesir University Medical SchoolDepartment of Cardiology, Izmir Katip Celebi University, Ataturk Training and Research HospitalAbstract We aimed to investigate the ability of the C-reactive protein-to-albumin ratio (CAR) to predict ascending aorta progression in patients with 40–50 mm diameter of ascending aortic dilatation. A total of 182 diagnosed patients with ascending aortic diameters of 40–50 mm were enrolled in this study. The study population was divided into tertiles based on yearly ascending aortic growth rate values. Group I (n = 137) was defined as a value in the lower 2 tertiles (ascending aorta growth ≤ 1.00 mm/year), and group II (n = 45) was defined as a value in the third tertile (ascending aorta growth > 1.00 mm/year). Hypertension, chronic obstructive pulmonary disease, positive family history, and CAR were found to be independent risk factors for ascending aorta growth > 1.00 mm/year. The area under the ROC curve (AUC) of CAR was 0.771(95% CI 0.689–0.854) for predicting ascending aorta growth > 1.00 mm/year. In patients with 40–50 mm ascending aneurysms, CAR may be useful to predict ascending aorta progression.https://doi.org/10.1186/s13019-022-02003-5InflammationAscending aortaAneurysmC-reactive protein-to-albumin ratioComputed tomography
spellingShingle Ahmet Dolapoglu
Eyüp Avci
Tuncay Kiris
The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mm
Journal of Cardiothoracic Surgery
Inflammation
Ascending aorta
Aneurysm
C-reactive protein-to-albumin ratio
Computed tomography
title The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mm
title_full The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mm
title_fullStr The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mm
title_full_unstemmed The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mm
title_short The predictive value of C-reactive protein to albümin ratio for ascending aort progression in patients with ascending aortic diameter of 40–50 mm
title_sort predictive value of c reactive protein to albumin ratio for ascending aort progression in patients with ascending aortic diameter of 40 50 mm
topic Inflammation
Ascending aorta
Aneurysm
C-reactive protein-to-albumin ratio
Computed tomography
url https://doi.org/10.1186/s13019-022-02003-5
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