A quantitative genetic model of background selection in humans.
Across the human genome, there are large-scale fluctuations in genetic diversity caused by the indirect effects of selection. This "linked selection signal" reflects the impact of selection according to the physical placement of functional regions and recombination rates along chromosomes....
Main Authors: | Vince Buffalo, Andrew D Kern |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-03-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1011144 |
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