First seroprevalence investigation of epizootic haemorrhagic disease virus in Libya
Background: Epizootic haemorrhagic disease (EHD) is a vector-borne viral disease of domestic and wild ruminants. EHD virus (EHDV) is transmitted by Culicoides spp. The EHDV is a member of the Orbivirus genus within the Reoviridae family. It shares many morphological and structural characteristics wi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Tripoli University
2021-06-01
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| Series: | Open Veterinary Journal |
| Subjects: | |
| Online Access: | https://www.openveterinaryjournal.com/OVJ-2021-03-043%20A.%20Mahmoud-2.pdf |
| _version_ | 1818387773008117760 |
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| author | Abdusalam Mahmoud Maria Luisa Danzetta Daria di Sabatino Massimo Spedicato Zakaria Alkhatal Abdunaser Dayhum Franceseco Tolari Mario Forzan Maurizio Mazzei Giovanni Savini |
| author_facet | Abdusalam Mahmoud Maria Luisa Danzetta Daria di Sabatino Massimo Spedicato Zakaria Alkhatal Abdunaser Dayhum Franceseco Tolari Mario Forzan Maurizio Mazzei Giovanni Savini |
| author_sort | Abdusalam Mahmoud |
| collection | DOAJ |
| description | Background: Epizootic haemorrhagic disease (EHD) is a vector-borne viral disease of domestic and wild ruminants. EHD virus (EHDV) is transmitted by Culicoides spp. The EHDV is a member of the Orbivirus genus within the Reoviridae family. It shares many morphological and structural characteristics with other members of the genus, such as the bluetongue virus (BTV), African horse sickness virus (AHSV) and equine encephalosis virus (EEV).
Aims: The purpose of our study was to investigate the epidemiological situation of EHDV in Libya in order to gain some knowledge about the presence of this virus in the country.
Methods: In this study, we investigated the seroprevalence of EHDV in Libya, testing 855 blood samples collected during 2015. The samples were collected from domestic ruminants (cattle, sheep and goats) originating from eleven provinces of Libya. Sera were tested by competitive enzyme-linked immunosorbent assays (c-ELISA ) and positive samples confirmed by serum neutralization test (SNT).
Results: The overall seroprevalence of EHDV was estimated to be 4% (95% CI=2.8%-5.4%). Small ruminant seroprevalence was significantly (p=0.016) higher than that found in cattle. Neutralizing antibodies against EHDV-6 were detected in a sheep from the western region of Libya.
Conclusion: This study suggests that EHDV has circulated or is circulating in Libya, and sheep could play an important role in the epidemiology of EHDV, and the virus may still be circulating in North Africa. |
| first_indexed | 2024-12-14T04:15:16Z |
| format | Article |
| id | doaj.art-5f11481f24a94fa29cffec56f21e9a83 |
| institution | Directory Open Access Journal |
| issn | 2218-6050 2218-6050 |
| language | English |
| last_indexed | 2024-12-14T04:15:16Z |
| publishDate | 2021-06-01 |
| publisher | Tripoli University |
| record_format | Article |
| series | Open Veterinary Journal |
| spelling | doaj.art-5f11481f24a94fa29cffec56f21e9a832022-12-21T23:17:32ZengTripoli UniversityOpen Veterinary Journal2218-60502218-60502021-06-0111230130810.5455/OVJ.2021.v11.i2.15First seroprevalence investigation of epizootic haemorrhagic disease virus in LibyaAbdusalam Mahmoud0https://orcid.org/0000-0002-2182-1647Maria Luisa Danzetta1Daria di Sabatino2Massimo Spedicato3Zakaria Alkhatal4Abdunaser Dayhum5Franceseco Tolari6Mario Forzan7Maurizio Mazzei8Giovanni Savini9Department of Preventive Medicine, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, LibyaIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise “G. Caporale”, (IZSAM), Teramo, ItalyIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise “G. Caporale”, (IZSAM), Teramo, ItalyIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise “G. Caporale”, (IZSAM), Teramo, ItalyNational Center of Animal Health, Tripoli, LibyaDepartment of Preventive Medicine, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, LibyaDepartment of Veterinary Science, University of Pisa, Pisa, ItalyDepartment of Veterinary Science, University of Pisa, Pisa, ItalyDepartment of Veterinary Science, University of Pisa, Pisa, ItalyIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise “G. Caporale”, (IZSAM), Teramo, ItalyBackground: Epizootic haemorrhagic disease (EHD) is a vector-borne viral disease of domestic and wild ruminants. EHD virus (EHDV) is transmitted by Culicoides spp. The EHDV is a member of the Orbivirus genus within the Reoviridae family. It shares many morphological and structural characteristics with other members of the genus, such as the bluetongue virus (BTV), African horse sickness virus (AHSV) and equine encephalosis virus (EEV). Aims: The purpose of our study was to investigate the epidemiological situation of EHDV in Libya in order to gain some knowledge about the presence of this virus in the country. Methods: In this study, we investigated the seroprevalence of EHDV in Libya, testing 855 blood samples collected during 2015. The samples were collected from domestic ruminants (cattle, sheep and goats) originating from eleven provinces of Libya. Sera were tested by competitive enzyme-linked immunosorbent assays (c-ELISA ) and positive samples confirmed by serum neutralization test (SNT). Results: The overall seroprevalence of EHDV was estimated to be 4% (95% CI=2.8%-5.4%). Small ruminant seroprevalence was significantly (p=0.016) higher than that found in cattle. Neutralizing antibodies against EHDV-6 were detected in a sheep from the western region of Libya. Conclusion: This study suggests that EHDV has circulated or is circulating in Libya, and sheep could play an important role in the epidemiology of EHDV, and the virus may still be circulating in North Africa.https://www.openveterinaryjournal.com/OVJ-2021-03-043%20A.%20Mahmoud-2.pdfehdseroprevalenceehdv-6 and risk factorslibya |
| spellingShingle | Abdusalam Mahmoud Maria Luisa Danzetta Daria di Sabatino Massimo Spedicato Zakaria Alkhatal Abdunaser Dayhum Franceseco Tolari Mario Forzan Maurizio Mazzei Giovanni Savini First seroprevalence investigation of epizootic haemorrhagic disease virus in Libya Open Veterinary Journal ehd seroprevalence ehdv-6 and risk factors libya |
| title | First seroprevalence investigation of epizootic haemorrhagic disease virus in Libya |
| title_full | First seroprevalence investigation of epizootic haemorrhagic disease virus in Libya |
| title_fullStr | First seroprevalence investigation of epizootic haemorrhagic disease virus in Libya |
| title_full_unstemmed | First seroprevalence investigation of epizootic haemorrhagic disease virus in Libya |
| title_short | First seroprevalence investigation of epizootic haemorrhagic disease virus in Libya |
| title_sort | first seroprevalence investigation of epizootic haemorrhagic disease virus in libya |
| topic | ehd seroprevalence ehdv-6 and risk factors libya |
| url | https://www.openveterinaryjournal.com/OVJ-2021-03-043%20A.%20Mahmoud-2.pdf |
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