Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus
Diabetes mellitus is a chronic complication that affects people of all ages. The increased prevalence of diabetes worldwide has led to the development of several synthetic drugs to tackle this health problem. Such drugs, although effective as antihyperglycemic agents, are accompanied by various side...
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| Format: | Article |
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MDPI AG
2022-07-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/13/4278 |
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| author | Prawej Ansari Samia Akther J. M. A. Hannan Veronique Seidel Nusrat Jahan Nujat Yasser H. A. Abdel-Wahab |
| author_facet | Prawej Ansari Samia Akther J. M. A. Hannan Veronique Seidel Nusrat Jahan Nujat Yasser H. A. Abdel-Wahab |
| author_sort | Prawej Ansari |
| collection | DOAJ |
| description | Diabetes mellitus is a chronic complication that affects people of all ages. The increased prevalence of diabetes worldwide has led to the development of several synthetic drugs to tackle this health problem. Such drugs, although effective as antihyperglycemic agents, are accompanied by various side effects, costly, and inaccessible to the majority of people living in underdeveloped countries. Medicinal plants have been used traditionally throughout the ages to treat various ailments due to their availability and safe nature. Medicinal plants are a rich source of phytochemicals that possess several health benefits. As diabetes continues to become prevalent, health care practitioners are considering plant-based medicines as a potential source of antidiabetic drugs due to their high potency and fewer side effects. To better understand the mechanism of action of medicinal plants, their active phytoconstituents are being isolated and investigated thoroughly. In this review article, we have focused on pharmacologically active phytomolecules isolated from medicinal plants presenting antidiabetic activity and the role they play in the treatment and management of diabetes. These natural compounds may represent as good candidates for a novel therapeutic approach and/or effective and alternative therapies for diabetes. |
| first_indexed | 2024-03-09T04:00:23Z |
| format | Article |
| id | doaj.art-5f115fda21c6449e98a005651fdde124 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T04:00:23Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-5f115fda21c6449e98a005651fdde1242023-12-03T14:14:14ZengMDPI AGMolecules1420-30492022-07-012713427810.3390/molecules27134278Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes MellitusPrawej Ansari0Samia Akther1J. M. A. Hannan2Veronique Seidel3Nusrat Jahan Nujat4Yasser H. A. Abdel-Wahab5Department of Pharmacy, Independent University, Dhaka 1229, BangladeshDepartment of Pharmacy, Independent University, Dhaka 1229, BangladeshDepartment of Pharmacy, Independent University, Dhaka 1229, BangladeshNatural Products Research Laboratory, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UKDepartment of Pharmacy, Independent University, Dhaka 1229, BangladeshSchool of Biomedical Sciences, Ulster University, Coleraine BT52 1SA, UKDiabetes mellitus is a chronic complication that affects people of all ages. The increased prevalence of diabetes worldwide has led to the development of several synthetic drugs to tackle this health problem. Such drugs, although effective as antihyperglycemic agents, are accompanied by various side effects, costly, and inaccessible to the majority of people living in underdeveloped countries. Medicinal plants have been used traditionally throughout the ages to treat various ailments due to their availability and safe nature. Medicinal plants are a rich source of phytochemicals that possess several health benefits. As diabetes continues to become prevalent, health care practitioners are considering plant-based medicines as a potential source of antidiabetic drugs due to their high potency and fewer side effects. To better understand the mechanism of action of medicinal plants, their active phytoconstituents are being isolated and investigated thoroughly. In this review article, we have focused on pharmacologically active phytomolecules isolated from medicinal plants presenting antidiabetic activity and the role they play in the treatment and management of diabetes. These natural compounds may represent as good candidates for a novel therapeutic approach and/or effective and alternative therapies for diabetes.https://www.mdpi.com/1420-3049/27/13/4278medicinal plantstraditional medicinephytoconstituentsdiabetespharmacology |
| spellingShingle | Prawej Ansari Samia Akther J. M. A. Hannan Veronique Seidel Nusrat Jahan Nujat Yasser H. A. Abdel-Wahab Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus Molecules medicinal plants traditional medicine phytoconstituents diabetes pharmacology |
| title | Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus |
| title_full | Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus |
| title_fullStr | Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus |
| title_full_unstemmed | Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus |
| title_short | Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus |
| title_sort | pharmacologically active phytomolecules isolated from traditional antidiabetic plants and their therapeutic role for the management of diabetes mellitus |
| topic | medicinal plants traditional medicine phytoconstituents diabetes pharmacology |
| url | https://www.mdpi.com/1420-3049/27/13/4278 |
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