Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis
Introduction Amphetamine-type stimulants (ATSs) are presenting a great challenge to global public health along with its worldwide abuse in recent years. Protracted amphetamine abstinence syndrome (PAAS) is one of the primary causes of relapse for ATS abusers during withdrawal. However, different con...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2023-04-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/4/e062491.full |
| _version_ | 1826986497121714176 |
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| author | Jun Luo Su Zhang Zhihan Chen Yulan Ren Yiwei Zeng Huan Ren |
| author_facet | Jun Luo Su Zhang Zhihan Chen Yulan Ren Yiwei Zeng Huan Ren |
| author_sort | Jun Luo |
| collection | DOAJ |
| description | Introduction Amphetamine-type stimulants (ATSs) are presenting a great challenge to global public health along with its worldwide abuse in recent years. Protracted amphetamine abstinence syndrome (PAAS) is one of the primary causes of relapse for ATS abusers during withdrawal. However, different conclusions are reached by previous trials. This study is designed to evaluate the efficacy and safety of acupuncture in treating PAAS.Methods and analysis Cochrane Central Register of Controlled Trials, PubMed, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, ProQuest Dissertation and Theses, Allied and Complementary Medicine Database (AMED), ClinicalTrials.gov and who.int/trialsearch will be searched from the inception to February 2023 and language will be restricted to English and Chinese. Eligible randomised controlled trials will be included. The primary outcome is the intensity of withdrawal syndrome. The secondary outcomes include: (1) intensity of pain, anxiety, depression and other associated symptoms; (2) number of participants with relapse; (3) retention of treatment and (4) nature and rate of adverse effects. Data synthesis will be performed by using RevMan (V.5.4). The quality of evidence will be evaluated by the Grading of Recommendations, Assessment, Development and Evaluation approach. This study will strictly adhere to the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines.Ethics and dissemination Ethical approval is not required as this is a systematic review and meta-analysis based on previously published studies that do not involve patients’ privacy. The results of this study will be disseminated in a peer-reviewed journal.PROSPERO registration number CRD42022297761. |
| first_indexed | 2024-04-09T16:49:02Z |
| format | Article |
| id | doaj.art-5f12830b7d724872975a8a5d9a1eea96 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2025-02-18T07:25:20Z |
| publishDate | 2023-04-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-5f12830b7d724872975a8a5d9a1eea962024-11-07T04:15:08ZengBMJ Publishing GroupBMJ Open2044-60552023-04-0113410.1136/bmjopen-2022-062491Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysisJun Luo0Su Zhang1Zhihan Chen2Yulan Ren3Yiwei Zeng4Huan Ren56 Department of Neurology, 404 Hospital, Mianyang, Sichuan, ChinaSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Chinese Classics, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaIntroduction Amphetamine-type stimulants (ATSs) are presenting a great challenge to global public health along with its worldwide abuse in recent years. Protracted amphetamine abstinence syndrome (PAAS) is one of the primary causes of relapse for ATS abusers during withdrawal. However, different conclusions are reached by previous trials. This study is designed to evaluate the efficacy and safety of acupuncture in treating PAAS.Methods and analysis Cochrane Central Register of Controlled Trials, PubMed, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, ProQuest Dissertation and Theses, Allied and Complementary Medicine Database (AMED), ClinicalTrials.gov and who.int/trialsearch will be searched from the inception to February 2023 and language will be restricted to English and Chinese. Eligible randomised controlled trials will be included. The primary outcome is the intensity of withdrawal syndrome. The secondary outcomes include: (1) intensity of pain, anxiety, depression and other associated symptoms; (2) number of participants with relapse; (3) retention of treatment and (4) nature and rate of adverse effects. Data synthesis will be performed by using RevMan (V.5.4). The quality of evidence will be evaluated by the Grading of Recommendations, Assessment, Development and Evaluation approach. This study will strictly adhere to the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines.Ethics and dissemination Ethical approval is not required as this is a systematic review and meta-analysis based on previously published studies that do not involve patients’ privacy. The results of this study will be disseminated in a peer-reviewed journal.PROSPERO registration number CRD42022297761.https://bmjopen.bmj.com/content/13/4/e062491.full |
| spellingShingle | Jun Luo Su Zhang Zhihan Chen Yulan Ren Yiwei Zeng Huan Ren Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis BMJ Open |
| title | Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis |
| title_full | Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis |
| title_fullStr | Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis |
| title_full_unstemmed | Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis |
| title_short | Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis |
| title_sort | acupuncture for protracted amphetamine abstinence syndrome study protocol for a systematic review and meta analysis |
| url | https://bmjopen.bmj.com/content/13/4/e062491.full |
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