Persistent infections in pediatrics: A modern view on the problem

The clinical and social impacts of persistent infections remain relevant. The main aspects of this pediatric problem are the epidemiology and pathogenesis of persistent infections, their clinical manifestations, possibilities for their treatment and prevention, and prediction of the active reproduct...

Full description

Bibliographic Details
Main Authors: A. D. Tsaregorodtsev, E. A. Ruzhitskaya, L. B. Kisteneva
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2017-04-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/445
Description
Summary:The clinical and social impacts of persistent infections remain relevant. The main aspects of this pediatric problem are the epidemiology and pathogenesis of persistent infections, their clinical manifestations, possibilities for their treatment and prevention, and prediction of the active reproduction of infectious agents. The issues of the human body’s interaction of persistent viruses with viruses that cause acute infectious diseases remain inadequately studied. There is no answer to the question as to the nature of this (synergistic, competitive) interaction or lack thereof. It is unclear how the persistent viruses interact with the host genome. The family and interfamily types of persistent infections, which is of key value in infection prevention in not only a baby, but also in a fetus, have not been adequately explored. This paper focuses on the most important and interesting medical and biological aspects of the problem of persistent infections and gives answers to some of them.
ISSN:1027-4065
2500-2228