Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants
The molecular mechanism of broad-spectrum neutralization of a rabbit monoclonal antibody 1H1 against Omicron sublineages is revealed by cryo-EM.
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04759-5 |
| _version_ | 1797849900136792064 |
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| author | Hangtian Guo Yixuan Yang Tiantian Zhao Yuchi Lu Yan Gao Tinghan Li Hang Xiao Xiaoyu Chu Le Zheng Wanting Li Hao Cheng Haibin Huang Yang Liu Yang Lou Henry C. Nguyen Chao Wu Yuxin Chen Haitao Yang Xiaoyun Ji |
| author_facet | Hangtian Guo Yixuan Yang Tiantian Zhao Yuchi Lu Yan Gao Tinghan Li Hang Xiao Xiaoyu Chu Le Zheng Wanting Li Hao Cheng Haibin Huang Yang Liu Yang Lou Henry C. Nguyen Chao Wu Yuxin Chen Haitao Yang Xiaoyun Ji |
| author_sort | Hangtian Guo |
| collection | DOAJ |
| description | The molecular mechanism of broad-spectrum neutralization of a rabbit monoclonal antibody 1H1 against Omicron sublineages is revealed by cryo-EM. |
| first_indexed | 2024-04-09T18:51:37Z |
| format | Article |
| id | doaj.art-5f181490fbe04e35828b3c8b432fc39c |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-09T18:51:37Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-5f181490fbe04e35828b3c8b432fc39c2023-04-09T11:24:27ZengNature PortfolioCommunications Biology2399-36422023-04-016111010.1038/s42003-023-04759-5Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variantsHangtian Guo0Yixuan Yang1Tiantian Zhao2Yuchi Lu3Yan Gao4Tinghan Li5Hang Xiao6Xiaoyu Chu7Le Zheng8Wanting Li9Hao Cheng10Haibin Huang11Yang Liu12Yang Lou13Henry C. Nguyen14Chao Wu15Yuxin Chen16Haitao Yang17Xiaoyun Ji18The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing UniversityThe State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing UniversityDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese MedicineShanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech UniversityShanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech UniversityThe State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing UniversityYurogen Biosystem LLCThe State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing UniversityThe State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing UniversityDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical UniversityYurogen Biosystem LLCYurogen Biosystem LLCYurogen Biosystem LLCYurogen Biosystem LLCShanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech UniversityDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese MedicineDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical SchoolShanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech UniversityThe State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing UniversityThe molecular mechanism of broad-spectrum neutralization of a rabbit monoclonal antibody 1H1 against Omicron sublineages is revealed by cryo-EM.https://doi.org/10.1038/s42003-023-04759-5 |
| spellingShingle | Hangtian Guo Yixuan Yang Tiantian Zhao Yuchi Lu Yan Gao Tinghan Li Hang Xiao Xiaoyu Chu Le Zheng Wanting Li Hao Cheng Haibin Huang Yang Liu Yang Lou Henry C. Nguyen Chao Wu Yuxin Chen Haitao Yang Xiaoyun Ji Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants Communications Biology |
| title | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants |
| title_full | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants |
| title_fullStr | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants |
| title_full_unstemmed | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants |
| title_short | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants |
| title_sort | mechanism of a rabbit monoclonal antibody broadly neutralizing sars cov 2 variants |
| url | https://doi.org/10.1038/s42003-023-04759-5 |
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