HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection

HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection

ABSTRACT Antiviral innate host defenses against acute viral infections include suppression of host protein synthesis to restrict viral protein production. Less is known about mechanisms by which viral pathogens subvert host antiviral innate responses for establishing their replication and disseminat...

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Bibliographic Details
Main Authors: Guochun Jiang, Clarissa Santos Rocha, Lauren A. Hirao, Erica A. Mendes, Yuyang Tang, George R. Thompson, Joseph K. Wong, Satya Dandekar
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Subjects:
ATF4
GCN2
HIV latency
HIV replication
HIV
Online Access:https://journals.asm.org/doi/10.1128/mBio.01518-16

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