Integrin α5β1, as a Receptor of Fibronectin, Binds the FbaA Protein of Group A <italic toggle="yes">Streptococcus</italic> To Initiate Autophagy during Infection

Integrin α5β1, as a Receptor of Fibronectin, Binds the FbaA Protein of Group A <italic toggle="yes">Streptococcus</italic> To Initiate Autophagy during Infection

ABSTRACT Group A Streptococcus (GAS), one of the most common extracellular pathogens, has been reported to invade epithelial and endothelial cells. Our results reveal that M1 GAS strain SF370 can be effectively eliminated by respiratory epithelial cells. Emerging evidence indicates that autophagy is...

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Bibliographic Details
Main Authors: Jiachao Wang, Meiqi Meng, Miao Li, Xiaofei Guan, Jianguo Liu, Xue Gao, Qingqing Sun, Jinquan Li, Cuiqing Ma, Lin Wei
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
autophagy
group A Streptococcus
FbaA protein
integrin α5β1
fibronectin
Online Access:https://journals.asm.org/doi/10.1128/mBio.00771-20

Internet

https://journals.asm.org/doi/10.1128/mBio.00771-20

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