A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series
BackgroundMotor dysfunction in the upper extremities after stroke prohibits people with stroke from being independent in daily living. The application of fNIRS to explore brain activity under rehabilitation intervention is a research focus on neurorehabilitation.ObjectiveThe purpose of this study wa...
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.907186/full |
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| author | ChaoJinZi Li ChaoJinZi Li Yih Wong Yih Wong Birgitta Langhammer Birgitta Langhammer FuBiao Huang FuBiao Huang XiaoXia Du XiaoXia Du YunLei Wang YunLei Wang HaoJie Zhang Tong Zhang Tong Zhang |
| author_facet | ChaoJinZi Li ChaoJinZi Li Yih Wong Yih Wong Birgitta Langhammer Birgitta Langhammer FuBiao Huang FuBiao Huang XiaoXia Du XiaoXia Du YunLei Wang YunLei Wang HaoJie Zhang Tong Zhang Tong Zhang |
| author_sort | ChaoJinZi Li |
| collection | DOAJ |
| description | BackgroundMotor dysfunction in the upper extremities after stroke prohibits people with stroke from being independent in daily living. The application of fNIRS to explore brain activity under rehabilitation intervention is a research focus on neurorehabilitation.ObjectiveThe purpose of this study was to explore, using a grip-release ring motor task, the activated changes of regions of interest and changes in motor function utilizing fNIRS technology and test scales on persons with stroke who received unilateral task-oriented therapy with a hand orthosis in the early subacute stroke period before and after intervention. The study aimed to find a sensitive motor task and region of interest first, then to evaluate the feasibility and mechanism of this rehabilitation method by utilizing fNIRS technology in the next randomized controlled trial.MethodsIn this case series, eight right-handed, right hemiplegia subacute stroke persons (6 males,2 females from age 47 to 72) were enrolled. They received 30 min of unilateral task-oriented therapy without orthosis and 30 min of unilateral task-oriented therapy with orthosis (5 days/week) for 4 weeks. Activated channel numbers and beta values based on oxygenated hemoglobin concentration change using a grip-release ring motor task were estimated with fNIRS. Clinical outcome measures, including grip strength evaluation, action research arm test, and Fugl-Meyer assessment of the arm, were evaluated at the same time.ResultsIndividual activation analysis showed that, after intervention, Subjects 1, 2, 6, 7, and 8 had the maximum mean beta value located in the left premotor cortex, while Subjects 4 and 5 had the maximum mean beta value located in the left sensorimotor cortex. The activation analysis of Subject 3 showed the maximum mean beta value located in the right premotor cortex. Deactivations of left sensorimotor cortex, left premotor cortex, and bilateral prefrontal cortex were observed after intervention which were different from other cases. Group activation analysis showed that bilateral cerebral hemispheres were activated in all eight participants, with right hemisphere and right supplementary motor cortex activated dominantly. After the intervention, the activation of bilateral hemispheres decreased but in different brain regions; there was a trend that the activation intensity of left sensorimotor cortex, right premotor cortex, and right prefrontal cortex decreased while activation intensity of left premotor cortex and left prefrontal cortex increased. Each participant demonstrated improvements in all the clinical test scales after intervention.ConclusionsLeft premotor cortex, left sensorimotor cortex, and right supplementary motor cortex may be the primary regions of interest. Grasp-release ring task was not appropriate to achieve our fNIRS research objective and a more sensitive motor task or more sensitive evaluating indicator should be used in further studies. |
| first_indexed | 2024-04-11T21:31:09Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-11T21:31:09Z |
| publishDate | 2022-08-01 |
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| series | Frontiers in Neurology |
| spelling | doaj.art-5f1aa6b022a7477c8f3f09d1eea31b7a2022-12-22T04:01:56ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-08-011310.3389/fneur.2022.907186907186A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case seriesChaoJinZi Li0ChaoJinZi Li1Yih Wong2Yih Wong3Birgitta Langhammer4Birgitta Langhammer5FuBiao Huang6FuBiao Huang7XiaoXia Du8XiaoXia Du9YunLei Wang10YunLei Wang11HaoJie Zhang12Tong Zhang13Tong Zhang14School of Rehabilitation Medicine, Capital Medical University, Beijing, ChinaDepartment of Neurological Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, ChinaDepartment of Research, Sunnaas Rehabilitation Hospital, Bjornemyr, NorwayFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, NorwayDepartment of Research, Sunnaas Rehabilitation Hospital, Bjornemyr, NorwayDepartment of Physiotherapy, Faculty of Health Science, OsloMet-Oslo Metropolitan University, Oslo, NorwaySchool of Rehabilitation Medicine, Capital Medical University, Beijing, ChinaDepartment of Occupational Therapy, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, ChinaSchool of Rehabilitation Medicine, Capital Medical University, Beijing, ChinaDepartment of Neurological Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, ChinaSchool of Rehabilitation Medicine, Capital Medical University, Beijing, ChinaDepartment of Neurological Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, ChinaSchool of Rehabilitation Medicine, Capital Medical University, Beijing, ChinaSchool of Rehabilitation Medicine, Capital Medical University, Beijing, ChinaDepartment of Neurological Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, ChinaBackgroundMotor dysfunction in the upper extremities after stroke prohibits people with stroke from being independent in daily living. The application of fNIRS to explore brain activity under rehabilitation intervention is a research focus on neurorehabilitation.ObjectiveThe purpose of this study was to explore, using a grip-release ring motor task, the activated changes of regions of interest and changes in motor function utilizing fNIRS technology and test scales on persons with stroke who received unilateral task-oriented therapy with a hand orthosis in the early subacute stroke period before and after intervention. The study aimed to find a sensitive motor task and region of interest first, then to evaluate the feasibility and mechanism of this rehabilitation method by utilizing fNIRS technology in the next randomized controlled trial.MethodsIn this case series, eight right-handed, right hemiplegia subacute stroke persons (6 males,2 females from age 47 to 72) were enrolled. They received 30 min of unilateral task-oriented therapy without orthosis and 30 min of unilateral task-oriented therapy with orthosis (5 days/week) for 4 weeks. Activated channel numbers and beta values based on oxygenated hemoglobin concentration change using a grip-release ring motor task were estimated with fNIRS. Clinical outcome measures, including grip strength evaluation, action research arm test, and Fugl-Meyer assessment of the arm, were evaluated at the same time.ResultsIndividual activation analysis showed that, after intervention, Subjects 1, 2, 6, 7, and 8 had the maximum mean beta value located in the left premotor cortex, while Subjects 4 and 5 had the maximum mean beta value located in the left sensorimotor cortex. The activation analysis of Subject 3 showed the maximum mean beta value located in the right premotor cortex. Deactivations of left sensorimotor cortex, left premotor cortex, and bilateral prefrontal cortex were observed after intervention which were different from other cases. Group activation analysis showed that bilateral cerebral hemispheres were activated in all eight participants, with right hemisphere and right supplementary motor cortex activated dominantly. After the intervention, the activation of bilateral hemispheres decreased but in different brain regions; there was a trend that the activation intensity of left sensorimotor cortex, right premotor cortex, and right prefrontal cortex decreased while activation intensity of left premotor cortex and left prefrontal cortex increased. Each participant demonstrated improvements in all the clinical test scales after intervention.ConclusionsLeft premotor cortex, left sensorimotor cortex, and right supplementary motor cortex may be the primary regions of interest. Grasp-release ring task was not appropriate to achieve our fNIRS research objective and a more sensitive motor task or more sensitive evaluating indicator should be used in further studies.https://www.frontiersin.org/articles/10.3389/fneur.2022.907186/fullstroketask-oriented therapyorthosisupper extremityneurorehabilitationnear-infrared spectroscopy |
| spellingShingle | ChaoJinZi Li ChaoJinZi Li Yih Wong Yih Wong Birgitta Langhammer Birgitta Langhammer FuBiao Huang FuBiao Huang XiaoXia Du XiaoXia Du YunLei Wang YunLei Wang HaoJie Zhang Tong Zhang Tong Zhang A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series Frontiers in Neurology stroke task-oriented therapy orthosis upper extremity neurorehabilitation near-infrared spectroscopy |
| title | A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series |
| title_full | A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series |
| title_fullStr | A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series |
| title_full_unstemmed | A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series |
| title_short | A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series |
| title_sort | study of dynamic hand orthosis combined with unilateral task oriented training in subacute stroke a functional near infrared spectroscopy case series |
| topic | stroke task-oriented therapy orthosis upper extremity neurorehabilitation near-infrared spectroscopy |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.907186/full |
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