Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing Bacteria
Gambierdiscus spp. are the major culprit responsible for global ciguatera fish poisoning (CFP). At present, the effects of microbiological factors on algal proliferation and toxin production are poorly understood. To evaluate the regulatory roles of quorum-sensing (QS) bacteria in the physiology of...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-06-01
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| Series: | Toxins |
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| Online Access: | http://www.mdpi.com/2072-6651/10/7/257 |
| _version_ | 1828371413944238080 |
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| author | Bo Wang Mimi Yao Jin Zhou Shangjin Tan Hui Jin Feng Zhang Yim Ling Mak Jiajun Wu Leo Lai Chan Zhonghua Cai |
| author_facet | Bo Wang Mimi Yao Jin Zhou Shangjin Tan Hui Jin Feng Zhang Yim Ling Mak Jiajun Wu Leo Lai Chan Zhonghua Cai |
| author_sort | Bo Wang |
| collection | DOAJ |
| description | Gambierdiscus spp. are the major culprit responsible for global ciguatera fish poisoning (CFP). At present, the effects of microbiological factors on algal proliferation and toxin production are poorly understood. To evaluate the regulatory roles of quorum-sensing (QS) bacteria in the physiology of Gambierdiscus, co-culture experiments with screened QS strains were conducted in this study. Except for the growth-inhibiting effect from the strain Marinobacter hydrocarbonoclasticus, the algal host generally displayed much higher growth potential and toxin production ability with the existence of QS strains. In addition, Bacillus anthracis particularly exhibited a broad-spectrum growth enhancement effect on various Gambierdiscus types, as well as a remarkable influence on algal toxicity. The variations of algal physiological status, including growth rate, chlorophyll content, and responsive behaviors, are potential reasons for the observed positive or negative affection. This study suggests that QS bacteria regulate the algal growth and toxin production. Based on the evidence, we further speculate that QS bacteria may contribute to the site-specific distribution of CFP risk through regulating the algal host biomass and toxicity. |
| first_indexed | 2024-04-14T06:49:27Z |
| format | Article |
| id | doaj.art-5f1e51939b27483aaee8d6769daea89b |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-14T06:49:27Z |
| publishDate | 2018-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-5f1e51939b27483aaee8d6769daea89b2022-12-22T02:07:04ZengMDPI AGToxins2072-66512018-06-0110725710.3390/toxins10070257toxins10070257Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing BacteriaBo Wang0Mimi Yao1Jin Zhou2Shangjin Tan3Hui Jin4Feng Zhang5Yim Ling Mak6Jiajun Wu7Leo Lai Chan8Zhonghua Cai9School of Life Science, Tsinghua University, Beijing 100084, ChinaCenter for Microalgal Biotechnology and Biofuels, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430070, ChinaShenzhen Public Platform of Screening & Application of Marine Microbial Resources, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, ChinaSchool of Life Science, Tsinghua University, Beijing 100084, ChinaSchool of Life Science, Tsinghua University, Beijing 100084, ChinaState Key Laboratory in Marine Pollution, City University of Hong Kong, Hong Kong 999077, ChinaState Key Laboratory in Marine Pollution, City University of Hong Kong, Hong Kong 999077, ChinaState Key Laboratory in Marine Pollution, City University of Hong Kong, Hong Kong 999077, ChinaState Key Laboratory in Marine Pollution, City University of Hong Kong, Hong Kong 999077, ChinaShenzhen Public Platform of Screening & Application of Marine Microbial Resources, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, ChinaGambierdiscus spp. are the major culprit responsible for global ciguatera fish poisoning (CFP). At present, the effects of microbiological factors on algal proliferation and toxin production are poorly understood. To evaluate the regulatory roles of quorum-sensing (QS) bacteria in the physiology of Gambierdiscus, co-culture experiments with screened QS strains were conducted in this study. Except for the growth-inhibiting effect from the strain Marinobacter hydrocarbonoclasticus, the algal host generally displayed much higher growth potential and toxin production ability with the existence of QS strains. In addition, Bacillus anthracis particularly exhibited a broad-spectrum growth enhancement effect on various Gambierdiscus types, as well as a remarkable influence on algal toxicity. The variations of algal physiological status, including growth rate, chlorophyll content, and responsive behaviors, are potential reasons for the observed positive or negative affection. This study suggests that QS bacteria regulate the algal growth and toxin production. Based on the evidence, we further speculate that QS bacteria may contribute to the site-specific distribution of CFP risk through regulating the algal host biomass and toxicity.http://www.mdpi.com/2072-6651/10/7/257Ciguatera fish poisoningGambierdiscusquorum sensingalgal–bacterial relationship |
| spellingShingle | Bo Wang Mimi Yao Jin Zhou Shangjin Tan Hui Jin Feng Zhang Yim Ling Mak Jiajun Wu Leo Lai Chan Zhonghua Cai Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing Bacteria Toxins Ciguatera fish poisoning Gambierdiscus quorum sensing algal–bacterial relationship |
| title | Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing Bacteria |
| title_full | Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing Bacteria |
| title_fullStr | Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing Bacteria |
| title_full_unstemmed | Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing Bacteria |
| title_short | Growth and Toxin Production of Gambierdiscus spp. Can Be Regulated by Quorum-Sensing Bacteria |
| title_sort | growth and toxin production of gambierdiscus spp can be regulated by quorum sensing bacteria |
| topic | Ciguatera fish poisoning Gambierdiscus quorum sensing algal–bacterial relationship |
| url | http://www.mdpi.com/2072-6651/10/7/257 |
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