Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel Entity

Invasive carcinoma of no special type (NST) or ductal carcinoma is the most common type of invasive breast cancers. Invasive lobular carcinoma (ILC) is the most common special variant amongst breast cancers that lacks some of the common features associated with breast cancers e.g. absence o...

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Main Authors: Md. Samim Iqbal, Urvashi Ghosh, Rina Mukherjee, Shyamalendu Mandal, Ankit Deb, Jayeeta Dutta
Format: Article
Language:English
Published: ADICHUNCHANAGIRI INSTITUTE OF MEDICAL SCIENCES 2023-12-01
Series:Journal of Medical Sciences and Health
Online Access:https://jmsh.ac.in/articles/invasive-lobular-carcinoma-of-breast-with-extracellular-mucin-a-novel-entity
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author Md. Samim Iqbal
Urvashi Ghosh
Rina Mukherjee
Shyamalendu Mandal
Ankit Deb
Jayeeta Dutta
author_facet Md. Samim Iqbal
Urvashi Ghosh
Rina Mukherjee
Shyamalendu Mandal
Ankit Deb
Jayeeta Dutta
author_sort Md. Samim Iqbal
collection DOAJ
description Invasive carcinoma of no special type (NST) or ductal carcinoma is the most common type of invasive breast cancers. Invasive lobular carcinoma (ILC) is the most common special variant amongst breast cancers that lacks some of the common features associated with breast cancers e.g. absence of desmoplastic reaction and infrequent mitosis. Some cases of ILC produce intracellular mucin that pushes the nucleus to one side, creating the characteristic signet ring cell morphology. Extracellular mucin secretion is essentially described in association with mucinous breast carcinoma and ductal carcinoma. Very few cases of ILC showing extracellular mucin has been reported in literature. Herein, such a rare case of classic lobular carcinoma is described, in a 70-year-old female who presented to the Surgical department of our hospital. Keywords: Breast cancer, Extracellular mucin, Invasive lobular carcinoma
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spelling doaj.art-5f1fe4a2419b4f9d87d1861ccd597b522024-01-31T13:08:12ZengADICHUNCHANAGIRI INSTITUTE OF MEDICAL SCIENCESJournal of Medical Sciences and Health2394-94812394-949X2023-12-019334334610.46347/jmsh.v9i3.22.469Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel EntityMd. Samim IqbalUrvashi GhoshRina Mukherjee Shyamalendu Mandal Ankit DebJayeeta Dutta Invasive carcinoma of no special type (NST) or ductal carcinoma is the most common type of invasive breast cancers. Invasive lobular carcinoma (ILC) is the most common special variant amongst breast cancers that lacks some of the common features associated with breast cancers e.g. absence of desmoplastic reaction and infrequent mitosis. Some cases of ILC produce intracellular mucin that pushes the nucleus to one side, creating the characteristic signet ring cell morphology. Extracellular mucin secretion is essentially described in association with mucinous breast carcinoma and ductal carcinoma. Very few cases of ILC showing extracellular mucin has been reported in literature. Herein, such a rare case of classic lobular carcinoma is described, in a 70-year-old female who presented to the Surgical department of our hospital. Keywords: Breast cancer, Extracellular mucin, Invasive lobular carcinomahttps://jmsh.ac.in/articles/invasive-lobular-carcinoma-of-breast-with-extracellular-mucin-a-novel-entity
spellingShingle Md. Samim Iqbal
Urvashi Ghosh
Rina Mukherjee
Shyamalendu Mandal
Ankit Deb
Jayeeta Dutta
Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel Entity
Journal of Medical Sciences and Health
title Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel Entity
title_full Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel Entity
title_fullStr Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel Entity
title_full_unstemmed Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel Entity
title_short Invasive Lobular Carcinoma of Breast with Extracellular Mucin: A Novel Entity
title_sort invasive lobular carcinoma of breast with extracellular mucin a novel entity
url https://jmsh.ac.in/articles/invasive-lobular-carcinoma-of-breast-with-extracellular-mucin-a-novel-entity
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AT urvashighosh invasivelobularcarcinomaofbreastwithextracellularmucinanovelentity
AT rinamukherjee invasivelobularcarcinomaofbreastwithextracellularmucinanovelentity
AT shyamalendumandal invasivelobularcarcinomaofbreastwithextracellularmucinanovelentity
AT ankitdeb invasivelobularcarcinomaofbreastwithextracellularmucinanovelentity
AT jayeetadutta invasivelobularcarcinomaofbreastwithextracellularmucinanovelentity