Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides

Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides

Enzymatic synthesis is an elegant biocompatible approach to complex compounds such as human milk oligosaccharides (HMOs). These compounds are vital for healthy neonatal development with a positive impact on the immune system. Although HMOs may be prepared by glycosyltransferases, this pathway is oft...

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Bibliographic Details
Main Authors: Pavlína Nekvasilová, Michaela Hovorková, Zuzana Mészáros, Lucie Petrásková, Helena Pelantová, Vladimír Křen, Kristýna Slámová, Pavla Bojarová
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
enzymatic synthesis
glycosidase
human milk oligosaccharide
mutagenesis
Online Access:https://www.mdpi.com/1422-0067/23/8/4106

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