New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling.

New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling.

Pharmacologic control of Cre-mediated recombination using tamoxifen-dependent activation of a Cre-estrogen receptor ligand binding domain fusion protein [CreER(T)] is widely used to modify and/or visualize cells in the mouse.We describe here two new mouse lines, constructed by gene targeting to the...

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Bibliographic Details
Main Authors: Tudor C Badea, Zhong L Hua, Philip M Smallwood, John Williams, Thomas Rotolo, Xin Ye, Jeremy Nathans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2775668?pdf=render

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