Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief Overview

ABSTRACT The aim of this review was to describe the current state-of-the-art regarding isolation, characterization and aging of adipose tissue-derived mesenchymal stem cells (ADSCs). Mesenchymal stem cells (MSCs) have recently received widespread attention because of their potential use in tissue-en...

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Main Authors: Ezzatollah Fathi, Raheleh Farahzadi
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2016-01-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100302&lng=en&tlng=en
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author Ezzatollah Fathi
Raheleh Farahzadi
author_facet Ezzatollah Fathi
Raheleh Farahzadi
author_sort Ezzatollah Fathi
collection DOAJ
description ABSTRACT The aim of this review was to describe the current state-of-the-art regarding isolation, characterization and aging of adipose tissue-derived mesenchymal stem cells (ADSCs). Mesenchymal stem cells (MSCs) have recently received widespread attention because of their potential use in tissue-engineering applications. Various studies have indicated that MSCs with a fibroblast-like morphology migrate to the sites of injury and help to regenerate damaged tissue. Over the past few years, it has been recognized that fat is not only an energy supply, but also a rich source of multipotent stem cells that can be easily harvested, isolated and selected as compared with other tissues. ADSCs are particularly interesting because of their rapid proliferation and multidirectional differentiation potential.
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spelling doaj.art-5f222ce3db0e418d95fd5eb008b2e48d2022-12-22T01:49:18ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1678-43242016-01-0159010.1590/1678-4324-2016150383S1516-89132016000100302Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief OverviewEzzatollah FathiRaheleh FarahzadiABSTRACT The aim of this review was to describe the current state-of-the-art regarding isolation, characterization and aging of adipose tissue-derived mesenchymal stem cells (ADSCs). Mesenchymal stem cells (MSCs) have recently received widespread attention because of their potential use in tissue-engineering applications. Various studies have indicated that MSCs with a fibroblast-like morphology migrate to the sites of injury and help to regenerate damaged tissue. Over the past few years, it has been recognized that fat is not only an energy supply, but also a rich source of multipotent stem cells that can be easily harvested, isolated and selected as compared with other tissues. ADSCs are particularly interesting because of their rapid proliferation and multidirectional differentiation potential.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100302&lng=en&tlng=enAdipose tissue-derived mesenchymal stem cellsadipose tissueisolationagingdifferentiation potential
spellingShingle Ezzatollah Fathi
Raheleh Farahzadi
Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief Overview
Brazilian Archives of Biology and Technology
Adipose tissue-derived mesenchymal stem cells
adipose tissue
isolation
aging
differentiation potential
title Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief Overview
title_full Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief Overview
title_fullStr Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief Overview
title_full_unstemmed Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief Overview
title_short Isolation, Culturing, Characterization and Aging of Adipose Tissue-derived Mesenchymal Stem Cells: A Brief Overview
title_sort isolation culturing characterization and aging of adipose tissue derived mesenchymal stem cells a brief overview
topic Adipose tissue-derived mesenchymal stem cells
adipose tissue
isolation
aging
differentiation potential
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100302&lng=en&tlng=en
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