Human pericytes degrade diverse α-synuclein aggregates.

Human pericytes degrade diverse α-synuclein aggregates.

Parkinson's disease (PD) is a progressive, neurodegenerative disorder characterised by the abnormal accumulation of α-synuclein (α-syn) aggregates. Central to disease progression is the gradual spread of pathological α-syn. α-syn aggregation is closely linked to progressive neuron loss. As such...

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Bibliographic Details
Main Authors: Birger Victor Dieriks, Blake Highet, Ania Alik, Tracy Bellande, Taylor J Stevenson, Victoria Low, Thomas I-H Park, Jason Correia, Patrick Schweder, Richard L M Faull, Ronald Melki, Maurice A Curtis, Mike Dragunow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0277658

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