Nuclear receptor corepressor 1 represses cardiac hypertrophy

Nuclear receptor corepressor 1 represses cardiac hypertrophy

Abstract The function of nuclear receptor corepressor 1 (NCoR1) in cardiomyocytes is unclear, and its physiological and pathological implications are unknown. Here, we found that cardiomyocyte‐specific NCoR1 knockout (CMNKO) mice manifested cardiac hypertrophy at baseline and had more severe cardiac...

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Bibliographic Details
Main Authors: Chao Li, Xue‐Nan Sun, Bo‐Yan Chen, Meng‐Ru Zeng, Lin‐Juan Du, Ting Liu, Hui‐Hui Gu, Yuan Liu, Yu‐Lin Li, Lu‐Jun Zhou, Xiao‐Jun Zheng, Yu‐Yao Zhang, Wu‐Chang Zhang, Yan Liu, Chaoji Shi, Shuai Shao, Xue‐Rui Shi, Yi Yi, Xu Liu, Jun Wang, Johan Auwerx, Zhao V Wang, Feng Jia, Ruo‐Gu Li, Sheng‐Zhong Duan
Format: Article
Language:English
Published: Springer Nature 2019-11-01
Series:EMBO Molecular Medicine
Subjects:
cardiac hypertrophy
class IIa HDACs
MEF2a
nuclear receptor corepressor 1
Online Access:https://doi.org/10.15252/emmm.201809127

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