Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection
Background Urinary tract infection (UTI) is common in children and, if incorrectly handled, may cause long-term complications, such as renal failure. The best test to diagnose UTIs is urine culture. However, urine culture is time-consuming, taking 3 - 5 days. Therefore, there is a need for faster, a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Indonesian Pediatric Society Publishing House
2011-10-01
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| Series: | Paediatrica Indonesiana |
| Subjects: | |
| Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/705 |
| _version_ | 1818215531285577728 |
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| author | Nurul Hidayah Pungky Ardani Kusum Noormanto Noormanto |
| author_facet | Nurul Hidayah Pungky Ardani Kusum Noormanto Noormanto |
| author_sort | Nurul Hidayah |
| collection | DOAJ |
| description | Background Urinary tract infection (UTI) is common in children
and, if incorrectly handled, may cause long-term complications,
such as renal failure. The best test to diagnose UTIs is urine
culture. However, urine culture is time-consuming, taking 3 - 5
days. Therefore, there is a need for faster, alternative methods.
Urinalysis is a common diagnostic test to establish the diagnosis
of UTI.
Objective To determine the sensitivity and
specificity of urine leukocytes, nitrite and leukocyte esterase for
UTIs diagnosis.
Methods We performed diagnostic tests at Dr. Sardjito Hospital,
Yogyakarta. We examined the presence of leukocytes in urine by microscopy,urinary nitrite and leukocyte esterase by dipstick test, while comparing to urine culture as the gold standard.
Results Two hundred children were included in our study. By
parallel test analysis, we found the sensitivity, specificity, positive
predictive value and negative predictive value of using all 3 tests
in combination were 95%, 59%, 74% and 89%, respectively
Conclusion Test for urine leukocytes, nitrite and leukocyte
esterase have high sensitivity but low specificity for diagnosing
UTIs. Therefore, negative results in these 3 tests do not rule
out the possibility of UTI in children. [Paediatr Indones.
2011 ;51;252-5]. |
| first_indexed | 2024-12-12T06:37:33Z |
| format | Article |
| id | doaj.art-5f36117d7dfa428e962d5274521fc010 |
| institution | Directory Open Access Journal |
| issn | 0030-9311 2338-476X |
| language | English |
| last_indexed | 2024-12-12T06:37:33Z |
| publishDate | 2011-10-01 |
| publisher | Indonesian Pediatric Society Publishing House |
| record_format | Article |
| series | Paediatrica Indonesiana |
| spelling | doaj.art-5f36117d7dfa428e962d5274521fc0102022-12-22T00:34:26ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2011-10-01515252510.14238/pi51.5.2011.252-5569Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infectionNurul Hidayah0Pungky Ardani Kusum1Noormanto Noormanto2Department of Child Health, Gadjah Mada University Medical School, Dr. Sardjito Hospital, Yogyakarta, Central JavaDepartment of Child Health, Gadjah Mada University Medical School, Dr. Sardjito Hospital, Yogyakarta, Central JavaDepartment of Child Health, Gadjah Mada University Medical School, Dr. Sardjito Hospital, Yogyakarta, Central JavaBackground Urinary tract infection (UTI) is common in children and, if incorrectly handled, may cause long-term complications, such as renal failure. The best test to diagnose UTIs is urine culture. However, urine culture is time-consuming, taking 3 - 5 days. Therefore, there is a need for faster, alternative methods. Urinalysis is a common diagnostic test to establish the diagnosis of UTI. Objective To determine the sensitivity and specificity of urine leukocytes, nitrite and leukocyte esterase for UTIs diagnosis. Methods We performed diagnostic tests at Dr. Sardjito Hospital, Yogyakarta. We examined the presence of leukocytes in urine by microscopy,urinary nitrite and leukocyte esterase by dipstick test, while comparing to urine culture as the gold standard. Results Two hundred children were included in our study. By parallel test analysis, we found the sensitivity, specificity, positive predictive value and negative predictive value of using all 3 tests in combination were 95%, 59%, 74% and 89%, respectively Conclusion Test for urine leukocytes, nitrite and leukocyte esterase have high sensitivity but low specificity for diagnosing UTIs. Therefore, negative results in these 3 tests do not rule out the possibility of UTI in children. [Paediatr Indones. 2011 ;51;252-5].https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/705urinary tract infectionurine dipstickurine microscopicurine culture |
| spellingShingle | Nurul Hidayah Pungky Ardani Kusum Noormanto Noormanto Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection Paediatrica Indonesiana urinary tract infection urine dipstick urine microscopic urine culture |
| title | Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection |
| title_full | Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection |
| title_fullStr | Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection |
| title_full_unstemmed | Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection |
| title_short | Diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection |
| title_sort | diagnostic tests of microscopic and urine dipstick examination in children with urinary tract infection |
| topic | urinary tract infection urine dipstick urine microscopic urine culture |
| url | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/705 |
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