Bacterial Species from Vaginal Microbiota Differently Affect the Production of the E6 and E7 Oncoproteins and of p53 and p-Rb Oncosuppressors in HPV16-Infected Cells

Bacterial Species from Vaginal Microbiota Differently Affect the Production of the E6 and E7 Oncoproteins and of p53 and p-Rb Oncosuppressors in HPV16-Infected Cells

Vaginal dysbiosis is characterized by a decrease in the relative abundance of <i>Lactobacillus</i> species in favor of other species. This condition facilitates infections by sexually transmitted pathogens including high risk (HR)-human papilloma viruses (HPVs) involved in the developmen...

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Bibliographic Details
Main Authors: Sabrina Nicolò, Alberto Antonelli, Michele Tanturli, Ilaria Baccani, Chiara Bonaiuto, Giuseppe Castronovo, Gian Maria Rossolini, G. Mattiuz, M. G. Torcia
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
HR-HPV (high-risk human papillomavirus)
CIN-1 (low grade of cervical intraepithelial neoplasia)
<i>Lactobacillus</i>
<i>Gardnerella</i>
<i>Megasphaera</i>
E6 and E7 oncoproteins
Online Access:https://www.mdpi.com/1422-0067/24/8/7173

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