Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis
Introduction: Quantification of D-dimer levels is a valuable test in orienting the diagnosis of deep vein thrombosis. Objectives: Determine D-dimer concentration and diagnostic value of D-dimer in patients with deep venous thrombosis. Methods: A descriptive, uncontrolled study was performed in 26...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Spanish |
| Published: |
ECIMED
2023-05-01
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| Series: | Revista Cubana de Medicina Militar |
| Subjects: | |
| Online Access: | https://revmedmilitar.sld.cu/index.php/mil/article/view/2728 |
| _version_ | 1797802309049122816 |
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| author | Van Nguyen-Thanh Phan De Nhi Nguyen Tri Dang-Minh Bui Minh Duc Tong Trung Hoang Nguyen Dung Thi-Ngoc Nguyen |
| author_facet | Van Nguyen-Thanh Phan De Nhi Nguyen Tri Dang-Minh Bui Minh Duc Tong Trung Hoang Nguyen Dung Thi-Ngoc Nguyen |
| author_sort | Van Nguyen-Thanh Phan |
| collection | DOAJ |
| description | Introduction: Quantification of D-dimer levels is a valuable test in orienting the diagnosis of deep vein thrombosis.
Objectives: Determine D-dimer concentration and diagnostic value of D-dimer in patients with deep venous thrombosis.
Methods: A descriptive, uncontrolled study was performed in 260 elderly patients at risk of deep vein thrombosis. All patients underwent quantitative D-dimer assay.
Results: The D-dimer concentration of patients with deep venous thrombosis had a median of 3106.5 ng/ml and was about 1.5 times higher than that of patients without deep venous thrombosis. With a threshold of D-dimer concentration of 500 ng/mL to determine deep venous thrombosis, the specificity of the method is low (16.51%), but the sensitivity is high (100%). And the positive predictive value is low (18.75%) but the negative predictive value is absolute (100%).
Conclusion: With a threshold of D-dimer concentration of 500 ng/mL to determine deep venous thrombosis, the specificity and positive predictive value of the method are low, but the sensitivity and negative predictive value are high. |
| first_indexed | 2024-03-13T05:03:44Z |
| format | Article |
| id | doaj.art-5f3e3c47aa684d0cbccdb6204bec2fc5 |
| institution | Directory Open Access Journal |
| issn | 1561-3046 |
| language | Spanish |
| last_indexed | 2024-03-13T05:03:44Z |
| publishDate | 2023-05-01 |
| publisher | ECIMED |
| record_format | Article |
| series | Revista Cubana de Medicina Militar |
| spelling | doaj.art-5f3e3c47aa684d0cbccdb6204bec2fc52023-06-17T04:25:56ZspaECIMEDRevista Cubana de Medicina Militar1561-30462023-05-01522e02302728e02302728770Concentration and the value of D-dimer in the diagnosis of deep vein thrombosisVan Nguyen-Thanh Phan0De Nhi Nguyen1Tri Dang-Minh Bui2Minh Duc Tong3Trung Hoang Nguyen4Dung Thi-Ngoc Nguyen5Pham Ngoc Thach University of MedicineGia Rai Medical CenterPham Ngoc Thach University of MedicineVietnam Military Medical UniversityVietnam Military Medical UniversityMilitary hospital 175Introduction: Quantification of D-dimer levels is a valuable test in orienting the diagnosis of deep vein thrombosis. Objectives: Determine D-dimer concentration and diagnostic value of D-dimer in patients with deep venous thrombosis. Methods: A descriptive, uncontrolled study was performed in 260 elderly patients at risk of deep vein thrombosis. All patients underwent quantitative D-dimer assay. Results: The D-dimer concentration of patients with deep venous thrombosis had a median of 3106.5 ng/ml and was about 1.5 times higher than that of patients without deep venous thrombosis. With a threshold of D-dimer concentration of 500 ng/mL to determine deep venous thrombosis, the specificity of the method is low (16.51%), but the sensitivity is high (100%). And the positive predictive value is low (18.75%) but the negative predictive value is absolute (100%). Conclusion: With a threshold of D-dimer concentration of 500 ng/mL to determine deep venous thrombosis, the specificity and positive predictive value of the method are low, but the sensitivity and negative predictive value are high.https://revmedmilitar.sld.cu/index.php/mil/article/view/2728d-dimer concentrationd-dimer diagnostic valuedeep vein thrombosis. |
| spellingShingle | Van Nguyen-Thanh Phan De Nhi Nguyen Tri Dang-Minh Bui Minh Duc Tong Trung Hoang Nguyen Dung Thi-Ngoc Nguyen Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis Revista Cubana de Medicina Militar d-dimer concentration d-dimer diagnostic value deep vein thrombosis. |
| title | Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis |
| title_full | Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis |
| title_fullStr | Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis |
| title_full_unstemmed | Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis |
| title_short | Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis |
| title_sort | concentration and the value of d dimer in the diagnosis of deep vein thrombosis |
| topic | d-dimer concentration d-dimer diagnostic value deep vein thrombosis. |
| url | https://revmedmilitar.sld.cu/index.php/mil/article/view/2728 |
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