Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer Tomography

Background: Percutaneous left atrial appendage closure (LAAC) requires accurate pre- and intraprocedural measurements, and multimodality imaging is an essential tool for guiding the procedure. Two-dimensional (2D TOE) and three-dimensional (3D TOE) transoesophageal echocardiography, cardiac computed...

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Main Authors: Gianpiero Italiano, Anna Maltagliati, Valentina Mantegazza, Laura Fusini, Maria Elisabetta Mancini, Alessio Gasperetti, Denise Brusoni, Francesca Susini, Alberto Formenti, Gianluca Pontone, Gaetano Fassini, Claudio Tondo, Mauro Pepi
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/10/12/1103
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author Gianpiero Italiano
Anna Maltagliati
Valentina Mantegazza
Laura Fusini
Maria Elisabetta Mancini
Alessio Gasperetti
Denise Brusoni
Francesca Susini
Alberto Formenti
Gianluca Pontone
Gaetano Fassini
Claudio Tondo
Mauro Pepi
author_facet Gianpiero Italiano
Anna Maltagliati
Valentina Mantegazza
Laura Fusini
Maria Elisabetta Mancini
Alessio Gasperetti
Denise Brusoni
Francesca Susini
Alberto Formenti
Gianluca Pontone
Gaetano Fassini
Claudio Tondo
Mauro Pepi
author_sort Gianpiero Italiano
collection DOAJ
description Background: Percutaneous left atrial appendage closure (LAAC) requires accurate pre- and intraprocedural measurements, and multimodality imaging is an essential tool for guiding the procedure. Two-dimensional (2D TOE) and three-dimensional (3D TOE) transoesophageal echocardiography, cardiac computed tomography (CCT), and conventional cardiac angiography (CCA) are commonly used to evaluate left atrial appendage (LAA) size. However, standardized approaches in measurement methods by different imaging modalities are lacking. The aims of the study were to evaluate the LAA dimension and morphology in patients undergoing LAAC and to compare data obtained by different imaging modalities: 2D and 3D TOE, CCT, and CCA. Methods: A total of 200 patients (mean age 70 ± 8 years, 128 males) were examined by different imaging techniques (161 2D TOE, 103 3D TOE, 98 CCT, and 200 CCA). Patients underwent preoperative CCT and intraoperative 2D and 3D TOE and CCA. Results: A significant correlation was found among all measurements obtained by different modalities. In particular, 3D TOE and CCT measurements were highly correlated with an excellent agreement for the landing zone (LZ) dimensions (LZ diameter: r = 0.87; LAA depth: r = 0.91, <i>p</i> < 0.001). Conclusions: Head-to-head comparison among imaging techniques (2D and 3D TOE, CCT, and CCA) showed a good correlation among LZ diameter measurements obtained by different imaging modalities, which is a parameter of paramount importance for the choice of the LAAC device size. LZ diameters and area by 3D TOE had the best correlation with CCT.
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spelling doaj.art-5f3f0ccef15a4e779df0e68d3b6dc4fe2023-11-21T01:11:27ZengMDPI AGDiagnostics2075-44182020-12-011012110310.3390/diagnostics10121103Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer TomographyGianpiero Italiano0Anna Maltagliati1Valentina Mantegazza2Laura Fusini3Maria Elisabetta Mancini4Alessio Gasperetti5Denise Brusoni6Francesca Susini7Alberto Formenti8Gianluca Pontone9Gaetano Fassini10Claudio Tondo11Mauro Pepi12Department of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, ItalyBackground: Percutaneous left atrial appendage closure (LAAC) requires accurate pre- and intraprocedural measurements, and multimodality imaging is an essential tool for guiding the procedure. Two-dimensional (2D TOE) and three-dimensional (3D TOE) transoesophageal echocardiography, cardiac computed tomography (CCT), and conventional cardiac angiography (CCA) are commonly used to evaluate left atrial appendage (LAA) size. However, standardized approaches in measurement methods by different imaging modalities are lacking. The aims of the study were to evaluate the LAA dimension and morphology in patients undergoing LAAC and to compare data obtained by different imaging modalities: 2D and 3D TOE, CCT, and CCA. Methods: A total of 200 patients (mean age 70 ± 8 years, 128 males) were examined by different imaging techniques (161 2D TOE, 103 3D TOE, 98 CCT, and 200 CCA). Patients underwent preoperative CCT and intraoperative 2D and 3D TOE and CCA. Results: A significant correlation was found among all measurements obtained by different modalities. In particular, 3D TOE and CCT measurements were highly correlated with an excellent agreement for the landing zone (LZ) dimensions (LZ diameter: r = 0.87; LAA depth: r = 0.91, <i>p</i> < 0.001). Conclusions: Head-to-head comparison among imaging techniques (2D and 3D TOE, CCT, and CCA) showed a good correlation among LZ diameter measurements obtained by different imaging modalities, which is a parameter of paramount importance for the choice of the LAAC device size. LZ diameters and area by 3D TOE had the best correlation with CCT.https://www.mdpi.com/2075-4418/10/12/1103left atrial appendage closureatrial fibrillation3D transoesophageal echocardiographycomputed tomography
spellingShingle Gianpiero Italiano
Anna Maltagliati
Valentina Mantegazza
Laura Fusini
Maria Elisabetta Mancini
Alessio Gasperetti
Denise Brusoni
Francesca Susini
Alberto Formenti
Gianluca Pontone
Gaetano Fassini
Claudio Tondo
Mauro Pepi
Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer Tomography
Diagnostics
left atrial appendage closure
atrial fibrillation
3D transoesophageal echocardiography
computed tomography
title Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer Tomography
title_full Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer Tomography
title_fullStr Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer Tomography
title_full_unstemmed Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer Tomography
title_short Multimodality Approach for Endovascular Left Atrial Appendage Closure: Head-To-Head Comparison among 2D and 3D Echocardiography, Angiography, and Computer Tomography
title_sort multimodality approach for endovascular left atrial appendage closure head to head comparison among 2d and 3d echocardiography angiography and computer tomography
topic left atrial appendage closure
atrial fibrillation
3D transoesophageal echocardiography
computed tomography
url https://www.mdpi.com/2075-4418/10/12/1103
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