Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study
Introduction: Coronavirus Disease-2019 (COVID-19) emerged as a global pandemic and was associated with various haematologic abnormalities. There are very few studies from India regarding the association between anaemia and disease severity of COVID-19. Aim: To check the prevalence of anaemia and it...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2023-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/18006/63141_CE[Ra1]_F[SK]_PF1(AG_SHU)_PFA(SS)_PB(AG_KM)_PN(KM).pdf |
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| author | Anirban Ghosh Rimi Som Sengupta Debjani Mallick Anirban Sarkar Samir Chakraborty |
| author_facet | Anirban Ghosh Rimi Som Sengupta Debjani Mallick Anirban Sarkar Samir Chakraborty |
| author_sort | Anirban Ghosh |
| collection | DOAJ |
| description | Introduction: Coronavirus Disease-2019 (COVID-19) emerged as a global pandemic and was associated with various haematologic abnormalities. There are very few studies from India regarding the association between anaemia and disease severity of COVID-19.
Aim: To check the prevalence of anaemia and its association with severity of disease among hospitalised COVID-19 patients.
Materials and Methods: This was a cross-sectional study involving 203 patients admitted in general ward and Intensive Care Unit (ICU) of a tertiary care hospital in eastern India. Complete blood count at admission along with other relevant clinical and laboratory parameters was noted. Haematological parameters of the patients were described and then correlated with disease severity and death. Spearman’s correlation and Chi-square test were used to determine the associations.
Results: Out of 203 patients with COVID-19,145 (71.4%) had anaemia. The study included 107 males (52.7%) and 96 females (47.3%), of which 77 (80%) females had anaemia compared to 68 (63.5%) males. Co-morbidities were present in 73 patients. Haemoglobin levels were significantly negatively correlated with disease severity (p<0.001). This was even true for patients without any other co-morbidities (p<0.05). Haemoglobin was also negatively correlated with deaths in this study (p<0.05).
Conclusion: The prevalence of anaemia in admitted patients of COVID-19 was very high and low haemoglobin levels were associated with more severe disease and death. So, low haemoglobin levels in COVID-19 may be considered as a risk factor for more severe disease and death. |
| first_indexed | 2024-03-13T07:06:31Z |
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| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-13T07:06:31Z |
| publishDate | 2023-05-01 |
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| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-5f3f9b35b3334d3eae8e514f3d5da7312023-06-06T09:43:23ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-05-01175OC38OC4110.7860/JCDR/2023/63141.18006Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional StudyAnirban Ghosh0Rimi Som Sengupta1Debjani Mallick2Anirban Sarkar3Samir Chakraborty4Associate Professor, Department of General Medicine, ESI-PGIMSR, ESIC Medical College and Hospital and ODC(EZ), Joka, Kolkata, West Bengal, India.Professor, Department of General Medicine, ESI-PGIMSR, ESIC Medical College and Hospital and ODC(EZ), Joka, Kolkata, West Bengal, India.Professor, Department of Pathology, ESI-PGIMSR, ESIC Medical College and Hospital and ODC(EZ), Joka Kolkata, West Bengal, India.Associate Professor, Department of General Medicine, ESI-PGIMSR, ESIC Medical College and Hospital and ODC(EZ), Joka, Kolkata, West Bengal, India.Associate Professor, Department of General Medicine, ESI-PGIMSR, ESIC Medical College and Hospital and ODC(EZ), Joka, Kolkata, West Bengal, India.Introduction: Coronavirus Disease-2019 (COVID-19) emerged as a global pandemic and was associated with various haematologic abnormalities. There are very few studies from India regarding the association between anaemia and disease severity of COVID-19. Aim: To check the prevalence of anaemia and its association with severity of disease among hospitalised COVID-19 patients. Materials and Methods: This was a cross-sectional study involving 203 patients admitted in general ward and Intensive Care Unit (ICU) of a tertiary care hospital in eastern India. Complete blood count at admission along with other relevant clinical and laboratory parameters was noted. Haematological parameters of the patients were described and then correlated with disease severity and death. Spearman’s correlation and Chi-square test were used to determine the associations. Results: Out of 203 patients with COVID-19,145 (71.4%) had anaemia. The study included 107 males (52.7%) and 96 females (47.3%), of which 77 (80%) females had anaemia compared to 68 (63.5%) males. Co-morbidities were present in 73 patients. Haemoglobin levels were significantly negatively correlated with disease severity (p<0.001). This was even true for patients without any other co-morbidities (p<0.05). Haemoglobin was also negatively correlated with deaths in this study (p<0.05). Conclusion: The prevalence of anaemia in admitted patients of COVID-19 was very high and low haemoglobin levels were associated with more severe disease and death. So, low haemoglobin levels in COVID-19 may be considered as a risk factor for more severe disease and death.https://jcdr.net/articles/PDF/18006/63141_CE[Ra1]_F[SK]_PF1(AG_SHU)_PFA(SS)_PB(AG_KM)_PN(KM).pdfblood countco-morbiditycoronavirusdeathsevere |
| spellingShingle | Anirban Ghosh Rimi Som Sengupta Debjani Mallick Anirban Sarkar Samir Chakraborty Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study Journal of Clinical and Diagnostic Research blood count co-morbidity coronavirus death severe |
| title | Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study |
| title_full | Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study |
| title_fullStr | Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study |
| title_full_unstemmed | Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study |
| title_short | Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study |
| title_sort | prevalence of anaemia and its association with severity of covid 19 among hospitalised patients a cross sectional study |
| topic | blood count co-morbidity coronavirus death severe |
| url | https://jcdr.net/articles/PDF/18006/63141_CE[Ra1]_F[SK]_PF1(AG_SHU)_PFA(SS)_PB(AG_KM)_PN(KM).pdf |
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