The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 Patients
Purpose: Smoking is an important risk factor for both the onset and poor prognosis for respiratory tract infections, chronic obstructive pulmonary disease, and lung cancer. There are no clear data on the relationship of COVID-19 to smoking status. In this study, it is aimed to evaluate the thiol and...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kirsehir Ahi Evran University
2022-12-01
|
| Series: | Ahi Evran Medical Journal |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/2331762 |
| _version_ | 1797921317397200896 |
|---|---|
| author | Funda EREN Esra FIRAT OĞUZ Salim NEŞELİOĞLU Rıdvan FIRAT Osman İNAN Emin GEMCİOĞLU Enes ŞAHİNER İhsan ATEŞ Özcan EREL |
| author_facet | Funda EREN Esra FIRAT OĞUZ Salim NEŞELİOĞLU Rıdvan FIRAT Osman İNAN Emin GEMCİOĞLU Enes ŞAHİNER İhsan ATEŞ Özcan EREL |
| author_sort | Funda EREN |
| collection | DOAJ |
| description | Purpose: Smoking is an important risk factor for both the onset and poor prognosis for respiratory tract infections, chronic obstructive pulmonary disease, and lung cancer. There are no clear data on the relationship of COVID-19 to smoking status. In this study, it is aimed to evaluate the thiol and ischemia modified albumin (IMA) levels of smokers, non-smokers and ex-smokers among COVID-19 patients.
Materials and methods: 145 volunteer patients diagnosed with COVID-19 according to PCR test results were included in the study. These patients were divided into three groups as non-smokers (group 1, 49 patients), smokers (group 2, 52 patients), and ex-smokers (group 3, 44 patients). Venous blood samples were taken from the patients into serum tubes for the measurement of thiol and IMA levels. All statistical evaluations were performed using SPSS software program.
Results: When the groups were compared, a significant difference was found between the thiol levels of group 1 and group 3, and between group 2 and group 3 (respectively, p=0.021, p=0.008). When the IMA levels were examined, a significant difference was found between the IMA levels of group 1 and group 3, and between group 2 and group 3 (respectively, p=0.009, p=0.005).
Conclusion: Smoking disrupts the balance between the oxidant-antioxidant system in the body, this balance is also disrupted in the regeneration process in the body in COVID-19 patients who have quit smoking. In addition, although the relationship between COVID-19 disease and smoking is still controversial, it is undisputed that smoking has harmful effects on all systems in the whole body. |
| first_indexed | 2024-04-10T14:14:12Z |
| format | Article |
| id | doaj.art-5f40734f717b492db98cf5b1e61d1b8c |
| institution | Directory Open Access Journal |
| issn | 2619-9203 |
| language | English |
| last_indexed | 2024-04-10T14:14:12Z |
| publishDate | 2022-12-01 |
| publisher | Kirsehir Ahi Evran University |
| record_format | Article |
| series | Ahi Evran Medical Journal |
| spelling | doaj.art-5f40734f717b492db98cf5b1e61d1b8c2023-02-15T16:09:35ZengKirsehir Ahi Evran UniversityAhi Evran Medical Journal2619-92032022-12-016333734210.46332/aemj.1093184The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 PatientsFunda EREN0https://orcid.org/0000-0002-8649-2493Esra FIRAT OĞUZ1https://orcid.org/0000-0002-8147-5379Salim NEŞELİOĞLU2https://orcid.org/0000-0002-0974-5717Rıdvan FIRAT3https://orcid.org/0000-0002-4655-0927Osman İNAN4https://orcid.org/0000-0002-8717-3013Emin GEMCİOĞLU5https://orcid.org/0000-0001-9751-8452Enes ŞAHİNER6https://orcid.org/0000-0003-4552-0387İhsan ATEŞ7https://orcid.org/0000-0003-2858-6229Özcan EREL8https://orcid.org/0000-0002-2996-3236Ankara Şehir HastanesiSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİYILDIRIM BEYAZIT ÜNİVERSİTESİ, TIP FAKÜLTESİSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜYILDIRIM BEYAZIT ÜNİVERSİTESİ, TIP FAKÜLTESİPurpose: Smoking is an important risk factor for both the onset and poor prognosis for respiratory tract infections, chronic obstructive pulmonary disease, and lung cancer. There are no clear data on the relationship of COVID-19 to smoking status. In this study, it is aimed to evaluate the thiol and ischemia modified albumin (IMA) levels of smokers, non-smokers and ex-smokers among COVID-19 patients. Materials and methods: 145 volunteer patients diagnosed with COVID-19 according to PCR test results were included in the study. These patients were divided into three groups as non-smokers (group 1, 49 patients), smokers (group 2, 52 patients), and ex-smokers (group 3, 44 patients). Venous blood samples were taken from the patients into serum tubes for the measurement of thiol and IMA levels. All statistical evaluations were performed using SPSS software program. Results: When the groups were compared, a significant difference was found between the thiol levels of group 1 and group 3, and between group 2 and group 3 (respectively, p=0.021, p=0.008). When the IMA levels were examined, a significant difference was found between the IMA levels of group 1 and group 3, and between group 2 and group 3 (respectively, p=0.009, p=0.005). Conclusion: Smoking disrupts the balance between the oxidant-antioxidant system in the body, this balance is also disrupted in the regeneration process in the body in COVID-19 patients who have quit smoking. In addition, although the relationship between COVID-19 disease and smoking is still controversial, it is undisputed that smoking has harmful effects on all systems in the whole body.https://dergipark.org.tr/tr/download/article-file/2331762antioxidantcoronavirüsinflammationoxidantsulfhydry |
| spellingShingle | Funda EREN Esra FIRAT OĞUZ Salim NEŞELİOĞLU Rıdvan FIRAT Osman İNAN Emin GEMCİOĞLU Enes ŞAHİNER İhsan ATEŞ Özcan EREL The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 Patients Ahi Evran Medical Journal antioxidant coronavirüs inflammation oxidant sulfhydry |
| title | The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 Patients |
| title_full | The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 Patients |
| title_fullStr | The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 Patients |
| title_full_unstemmed | The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 Patients |
| title_short | The Evaluation of the Relationship Between Smoking Status and Thiol and Ischemia Modified Albumin Levels of COVID-19 Patients |
| title_sort | evaluation of the relationship between smoking status and thiol and ischemia modified albumin levels of covid 19 patients |
| topic | antioxidant coronavirüs inflammation oxidant sulfhydry |
| url | https://dergipark.org.tr/tr/download/article-file/2331762 |
| work_keys_str_mv | AT fundaeren theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT esrafiratoguz theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT salimneselioglu theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT rıdvanfirat theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT osmaninan theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT emingemcioglu theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT enessahiner theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT ihsanates theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT ozcanerel theevaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT fundaeren evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT esrafiratoguz evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT salimneselioglu evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT rıdvanfirat evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT osmaninan evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT emingemcioglu evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT enessahiner evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT ihsanates evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients AT ozcanerel evaluationoftherelationshipbetweensmokingstatusandthiolandischemiamodifiedalbuminlevelsofcovid19patients |