<i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral Species
Viruses are the most diverse and abundant microorganisms on earth, highly adaptive to a wide range of hosts. Viral diversity within invertebrate hosts has gained notoriety in recent years in public health as several such viruses have been of medical importance. <i>Aedes aegypti</i> serve...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/12/8/866 |
| _version_ | 1797559466839769088 |
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| author | Geovani de Oliveira Ribeiro Vanessa S. Morais Fred Julio Costa Monteiro Edcelha Soares D’Athaide Ribeiro Marlisson Octavio da S Rego Raimundo Nonato Picanço Souto Fabiola Villanova Roozbeh Tahmasebi Philip Michael Hefford Xutao Deng Eric Delwart Ester Cerdeira Sabino Licia Natal Fernandes Antonio Charlys da Costa Élcio Leal |
| author_facet | Geovani de Oliveira Ribeiro Vanessa S. Morais Fred Julio Costa Monteiro Edcelha Soares D’Athaide Ribeiro Marlisson Octavio da S Rego Raimundo Nonato Picanço Souto Fabiola Villanova Roozbeh Tahmasebi Philip Michael Hefford Xutao Deng Eric Delwart Ester Cerdeira Sabino Licia Natal Fernandes Antonio Charlys da Costa Élcio Leal |
| author_sort | Geovani de Oliveira Ribeiro |
| collection | DOAJ |
| description | Viruses are the most diverse and abundant microorganisms on earth, highly adaptive to a wide range of hosts. Viral diversity within invertebrate hosts has gained notoriety in recent years in public health as several such viruses have been of medical importance. <i>Aedes aegypti</i> serves as a vector for several viruses that have caused epidemics within the last year throughout Brazil; including Dengue, Zika and Chikungunya. This study aimed to identify new viral agents within <i>Aedes aegypti</i> mosquito in a city of the Amazonian region, where it is highly endemic. Metagenomic investigation was performed on 60 mosquito pools and viral RNA sequences present in their microbiota were characterized using genomic and phylogenetic tools. In total, we identified five putative novel virus species related to the <i>Sobemovirus</i> genus, <i>Iflavirus</i> genus and <i>Permutatetraviridae</i> family. These findings indicate a diverse taxonomy of viruses present in the mosquito microbiota of the Amazon, the region with the greatest invertebrate diversity in the world. |
| first_indexed | 2024-03-10T17:45:51Z |
| format | Article |
| id | doaj.art-5f40a8c5c1b84860ad5a6654f6266e4a |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T17:45:51Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-5f40a8c5c1b84860ad5a6654f6266e4a2023-11-20T09:31:35ZengMDPI AGViruses1999-49152020-08-0112886610.3390/v12080866<i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral SpeciesGeovani de Oliveira Ribeiro0Vanessa S. Morais1Fred Julio Costa Monteiro2Edcelha Soares D’Athaide Ribeiro3Marlisson Octavio da S Rego4Raimundo Nonato Picanço Souto5Fabiola Villanova6Roozbeh Tahmasebi7Philip Michael Hefford8Xutao Deng9Eric Delwart10Ester Cerdeira Sabino11Licia Natal Fernandes12Antonio Charlys da Costa13Élcio Leal14Institute of Biological Sciences, Federal University of Pará, Belém, Pará, 66075-000, BrazilInstitute of Tropical Medicine, University of São Paulo, São Paulo 05403-000, BrazilPublic Health Laboratory of Amapa-LACEN/AP, Health Surveillance Superintendence of Amapa, Macapa 68905-230, Amapa, BrazilPublic Health Laboratory of Amapa-LACEN/AP, Health Surveillance Superintendence of Amapa, Macapa 68905-230, Amapa, BrazilPublic Health Laboratory of Amapa-LACEN/AP, Health Surveillance Superintendence of Amapa, Macapa 68905-230, Amapa, BrazilArthropoda Laboratory, Federal University of Amapa, Macapa 68905-230, Amapa, BrazilInstitute of Biological Sciences, Federal University of Pará, Belém, Pará, 66075-000, BrazilInstitute of Tropical Medicine, University of São Paulo, São Paulo 05403-000, BrazilUniversity Hospitals Plymouth NHS Trust, Derriford Road, Crownhill, Plymouth PL6 8DH, UKVitalant Research Institute, 270 Masonic Avenue, San Francisco, CA 94118-4417, USAVitalant Research Institute, 270 Masonic Avenue, San Francisco, CA 94118-4417, USAInstitute of Tropical Medicine, University of São Paulo, São Paulo 05403-000, BrazilInstitute of Tropical Medicine, University of São Paulo, São Paulo 05403-000, BrazilInstitute of Tropical Medicine, University of São Paulo, São Paulo 05403-000, BrazilInstitute of Biological Sciences, Federal University of Pará, Belém, Pará, 66075-000, BrazilViruses are the most diverse and abundant microorganisms on earth, highly adaptive to a wide range of hosts. Viral diversity within invertebrate hosts has gained notoriety in recent years in public health as several such viruses have been of medical importance. <i>Aedes aegypti</i> serves as a vector for several viruses that have caused epidemics within the last year throughout Brazil; including Dengue, Zika and Chikungunya. This study aimed to identify new viral agents within <i>Aedes aegypti</i> mosquito in a city of the Amazonian region, where it is highly endemic. Metagenomic investigation was performed on 60 mosquito pools and viral RNA sequences present in their microbiota were characterized using genomic and phylogenetic tools. In total, we identified five putative novel virus species related to the <i>Sobemovirus</i> genus, <i>Iflavirus</i> genus and <i>Permutatetraviridae</i> family. These findings indicate a diverse taxonomy of viruses present in the mosquito microbiota of the Amazon, the region with the greatest invertebrate diversity in the world.https://www.mdpi.com/1999-4915/12/8/866microbiotaviral diversityNGSinsect-virus<i>Aedes aegypti</i>Amazon |
| spellingShingle | Geovani de Oliveira Ribeiro Vanessa S. Morais Fred Julio Costa Monteiro Edcelha Soares D’Athaide Ribeiro Marlisson Octavio da S Rego Raimundo Nonato Picanço Souto Fabiola Villanova Roozbeh Tahmasebi Philip Michael Hefford Xutao Deng Eric Delwart Ester Cerdeira Sabino Licia Natal Fernandes Antonio Charlys da Costa Élcio Leal <i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral Species Viruses microbiota viral diversity NGS insect-virus <i>Aedes aegypti</i> Amazon |
| title | <i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral Species |
| title_full | <i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral Species |
| title_fullStr | <i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral Species |
| title_full_unstemmed | <i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral Species |
| title_short | <i>Aedes aegypti</i> from Amazon Basin Harbor High Diversity of Novel Viral Species |
| title_sort | i aedes aegypti i from amazon basin harbor high diversity of novel viral species |
| topic | microbiota viral diversity NGS insect-virus <i>Aedes aegypti</i> Amazon |
| url | https://www.mdpi.com/1999-4915/12/8/866 |
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