Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels

BackgroundGlucose and lipid tolerance reportedly exhibit diurnal variations, being lower in the evening than in the morning. Therefore, the effects of exercise on glucose and blood lipid levels at different times of the day may differ. This study aimed to investigate the effects of short-term endura...

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Main Authors: Hyeon-Ki Kim, Shota Furuhashi, Masaki Takahashi, Hanako Chijiki, Takuya Nanba, Takayuki Inami, Zsolt Radak, Shizuo Sakamoto, Shigenobu Shibata
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.957239/full
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author Hyeon-Ki Kim
Hyeon-Ki Kim
Shota Furuhashi
Masaki Takahashi
Hanako Chijiki
Takuya Nanba
Takayuki Inami
Zsolt Radak
Zsolt Radak
Shizuo Sakamoto
Shigenobu Shibata
author_facet Hyeon-Ki Kim
Hyeon-Ki Kim
Shota Furuhashi
Masaki Takahashi
Hanako Chijiki
Takuya Nanba
Takayuki Inami
Zsolt Radak
Zsolt Radak
Shizuo Sakamoto
Shigenobu Shibata
author_sort Hyeon-Ki Kim
collection DOAJ
description BackgroundGlucose and lipid tolerance reportedly exhibit diurnal variations, being lower in the evening than in the morning. Therefore, the effects of exercise on glucose and blood lipid levels at different times of the day may differ. This study aimed to investigate the effects of short-term endurance exercise intervention in the morning versus late afternoon on 24-h blood glucose variability and blood lipid levels.MethodsTwelve healthy young men participated in a randomized crossover trial. The participants were assigned to morning (09:00–11:00) or late afternoon (16:00–18:00) endurance exercise for a week, consisting of supervised exercise sessions on Mondays, Wednesdays, and Fridays. In the morning and evening trials, the participants walked for 60 min on a treadmill at approximately 60% of maximal oxygen uptake (VO2max). Following a 2-week wash-out period, the participants performed the exercise training regimen at another time point. Continuous glucose monitoring was used to evaluate blood glucose fluctuations during each 24-h trial period. Blood samples were collected before and after each intervention to examine blood lipid and hormonal responses.ResultsExamination of the area under the curve (AUC) of the glucose level changes for 24 h after the late afternoon versus morning exercise intervention revealed significantly lower values for the former versus the latter (P < 0.01). The AUC of glucose level changes after each meal was also lower after the late afternoon versus morning intervention, and significantly lower values were observed in the late afternoon versus morning trial for breakfast and dinner (P < 0.05, P < 0.01). In addition, a significant decrease in triglycerides (TG) and TG/high-density lipoprotein cholesterol (HDL-C) was noted after versus before the late afternoon intervention (P < 0.05).ConclusionsThese results suggest that late afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and triglyceride levels.
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spelling doaj.art-5f4c4469e41a4a44885ab44ee9f9d79e2022-12-22T03:01:44ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-07-011310.3389/fendo.2022.957239957239Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levelsHyeon-Ki Kim0Hyeon-Ki Kim1Shota Furuhashi2Masaki Takahashi3Hanako Chijiki4Takuya Nanba5Takayuki Inami6Zsolt Radak7Zsolt Radak8Shizuo Sakamoto9Shigenobu Shibata10Faculty of Science and Engineering, Waseda University, Tokyo, JapanInstitute of Physical Education, Keio University, Yokohama, JapanGraduate School of Advanced Science and Engineering, Waseda University, Tokyo, JapanInstitute for Liberal Arts, Tokyo Institute of Technology, Tokyo, JapanGraduate School of Advanced Science and Engineering, Waseda University, Tokyo, JapanGraduate School of Advanced Science and Engineering, Waseda University, Tokyo, JapanInstitute of Physical Education, Keio University, Yokohama, JapanFaculty of Sport Sciences, Waseda University, Saitama, JapanResearch Center for Molecular Exercise Science, University of Physical Education, Budapest, HungaryFaculty of Sport Sciences, Surugadai University, Saitama, JapanFaculty of Science and Engineering, Waseda University, Tokyo, JapanBackgroundGlucose and lipid tolerance reportedly exhibit diurnal variations, being lower in the evening than in the morning. Therefore, the effects of exercise on glucose and blood lipid levels at different times of the day may differ. This study aimed to investigate the effects of short-term endurance exercise intervention in the morning versus late afternoon on 24-h blood glucose variability and blood lipid levels.MethodsTwelve healthy young men participated in a randomized crossover trial. The participants were assigned to morning (09:00–11:00) or late afternoon (16:00–18:00) endurance exercise for a week, consisting of supervised exercise sessions on Mondays, Wednesdays, and Fridays. In the morning and evening trials, the participants walked for 60 min on a treadmill at approximately 60% of maximal oxygen uptake (VO2max). Following a 2-week wash-out period, the participants performed the exercise training regimen at another time point. Continuous glucose monitoring was used to evaluate blood glucose fluctuations during each 24-h trial period. Blood samples were collected before and after each intervention to examine blood lipid and hormonal responses.ResultsExamination of the area under the curve (AUC) of the glucose level changes for 24 h after the late afternoon versus morning exercise intervention revealed significantly lower values for the former versus the latter (P < 0.01). The AUC of glucose level changes after each meal was also lower after the late afternoon versus morning intervention, and significantly lower values were observed in the late afternoon versus morning trial for breakfast and dinner (P < 0.05, P < 0.01). In addition, a significant decrease in triglycerides (TG) and TG/high-density lipoprotein cholesterol (HDL-C) was noted after versus before the late afternoon intervention (P < 0.05).ConclusionsThese results suggest that late afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and triglyceride levels.https://www.frontiersin.org/articles/10.3389/fendo.2022.957239/fullchrono-exerciseexercise timingendurance exerciseglucose levelstriglycerides
spellingShingle Hyeon-Ki Kim
Hyeon-Ki Kim
Shota Furuhashi
Masaki Takahashi
Hanako Chijiki
Takuya Nanba
Takayuki Inami
Zsolt Radak
Zsolt Radak
Shizuo Sakamoto
Shigenobu Shibata
Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels
Frontiers in Endocrinology
chrono-exercise
exercise timing
endurance exercise
glucose levels
triglycerides
title Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels
title_full Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels
title_fullStr Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels
title_full_unstemmed Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels
title_short Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels
title_sort late afternoon endurance exercise is more effective than morning endurance exercise at improving 24 h glucose and blood lipid levels
topic chrono-exercise
exercise timing
endurance exercise
glucose levels
triglycerides
url https://www.frontiersin.org/articles/10.3389/fendo.2022.957239/full
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