Biosensors-on-Chip: An Up-to-Date Review
Generally, biosensors are designed to translate physical, chemical, or biological events into measurable signals, thus offering qualitative and/or quantitative information regarding the target analytes. While the biosensor field has received considerable scientific interest, integrating this technol...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/24/6013 |
| _version_ | 1797544138477928448 |
|---|---|
| author | Cristina Chircov Alexandra Cătălina Bîrcă Alexandru Mihai Grumezescu Ecaterina Andronescu |
| author_facet | Cristina Chircov Alexandra Cătălina Bîrcă Alexandru Mihai Grumezescu Ecaterina Andronescu |
| author_sort | Cristina Chircov |
| collection | DOAJ |
| description | Generally, biosensors are designed to translate physical, chemical, or biological events into measurable signals, thus offering qualitative and/or quantitative information regarding the target analytes. While the biosensor field has received considerable scientific interest, integrating this technology with microfluidics could further bring significant improvements in terms of sensitivity and specificity, resolution, automation, throughput, reproducibility, reliability, and accuracy. In this manner, biosensors-on-chip (BoC) could represent the bridging gap between diagnostics in central laboratories and diagnostics at the patient bedside, bringing substantial advancements in point-of-care (PoC) diagnostic applications. In this context, the aim of this manuscript is to provide an up-to-date overview of BoC system development and their most recent application towards the diagnosis of cancer, infectious diseases, and neurodegenerative disorders. |
| first_indexed | 2024-03-10T13:56:09Z |
| format | Article |
| id | doaj.art-5f4ce0e93d534af29a25eaa247ef6e9b |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T13:56:09Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-5f4ce0e93d534af29a25eaa247ef6e9b2023-11-21T01:35:28ZengMDPI AGMolecules1420-30492020-12-012524601310.3390/molecules25246013Biosensors-on-Chip: An Up-to-Date ReviewCristina Chircov0Alexandra Cătălina Bîrcă1Alexandru Mihai Grumezescu2Ecaterina Andronescu3Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, RomaniaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, RomaniaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, RomaniaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, RomaniaGenerally, biosensors are designed to translate physical, chemical, or biological events into measurable signals, thus offering qualitative and/or quantitative information regarding the target analytes. While the biosensor field has received considerable scientific interest, integrating this technology with microfluidics could further bring significant improvements in terms of sensitivity and specificity, resolution, automation, throughput, reproducibility, reliability, and accuracy. In this manner, biosensors-on-chip (BoC) could represent the bridging gap between diagnostics in central laboratories and diagnostics at the patient bedside, bringing substantial advancements in point-of-care (PoC) diagnostic applications. In this context, the aim of this manuscript is to provide an up-to-date overview of BoC system development and their most recent application towards the diagnosis of cancer, infectious diseases, and neurodegenerative disorders.https://www.mdpi.com/1420-3049/25/24/6013biosensors on a chipbiosensorsmicrofluidicspoint-of-carediagnostics |
| spellingShingle | Cristina Chircov Alexandra Cătălina Bîrcă Alexandru Mihai Grumezescu Ecaterina Andronescu Biosensors-on-Chip: An Up-to-Date Review Molecules biosensors on a chip biosensors microfluidics point-of-care diagnostics |
| title | Biosensors-on-Chip: An Up-to-Date Review |
| title_full | Biosensors-on-Chip: An Up-to-Date Review |
| title_fullStr | Biosensors-on-Chip: An Up-to-Date Review |
| title_full_unstemmed | Biosensors-on-Chip: An Up-to-Date Review |
| title_short | Biosensors-on-Chip: An Up-to-Date Review |
| title_sort | biosensors on chip an up to date review |
| topic | biosensors on a chip biosensors microfluidics point-of-care diagnostics |
| url | https://www.mdpi.com/1420-3049/25/24/6013 |
| work_keys_str_mv | AT cristinachircov biosensorsonchipanuptodatereview AT alexandracatalinabirca biosensorsonchipanuptodatereview AT alexandrumihaigrumezescu biosensorsonchipanuptodatereview AT ecaterinaandronescu biosensorsonchipanuptodatereview |