Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys

Magnesium alloys are attractive candidates for use as temporary fixation devices in osteosynthesis because they have a density and Young’s modulus similar to those of cortical bone. One of the main requirements for biodegradable implants is its substitution by tissues during the healing process. In...

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Main Authors: Viacheslav Bazhenov, Anna Li, Stanislav Tavolzhanskii, Andrey Bazlov, Natalia Tabachkova, Andrey Koltygin, Alexander Komissarov, Kwang Seon Shin
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/15/19/6849
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author Viacheslav Bazhenov
Anna Li
Stanislav Tavolzhanskii
Andrey Bazlov
Natalia Tabachkova
Andrey Koltygin
Alexander Komissarov
Kwang Seon Shin
author_facet Viacheslav Bazhenov
Anna Li
Stanislav Tavolzhanskii
Andrey Bazlov
Natalia Tabachkova
Andrey Koltygin
Alexander Komissarov
Kwang Seon Shin
author_sort Viacheslav Bazhenov
collection DOAJ
description Magnesium alloys are attractive candidates for use as temporary fixation devices in osteosynthesis because they have a density and Young’s modulus similar to those of cortical bone. One of the main requirements for biodegradable implants is its substitution by tissues during the healing process. In this article, the Mg–Zn–Ga–(Y) alloys were investigated that potentially can increase the bone growth rate by release of Ga ions during the degradation process. Previously, the effectiveness of Ga ions on bone tissue regeneration has been proved by clinical tests. This work is the first systematic study on the microstructure and mechanical properties of Mg–Zn–Y alloys containing Ga as an additional major alloying element prepared by the hot-extrusion process. The microstructure and phase composition of the Mg–Zn–Ga–(Y) alloys in as-cast, heat-treated, and extruded conditions were analyzed. In addition, it was shown that the use of hot extrusion produces Mg–Zn–Ga–(Y) alloys with favorable mechanical properties. The tensile yield strength, ultimate tensile strength, and elongation at fracture of the MgZn4Ga4 alloy extruded at 150 °C were 256 MPa, 343 MPa, and 14.2%, respectively. Overall, MgZn4Ga4 alloy is a perspective for applications in implants for osteosynthesis with improved bone regeneration ability.
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spelling doaj.art-5f4d6eb628354ab791727be7fb95d7892023-11-23T20:57:51ZengMDPI AGMaterials1996-19442022-10-011519684910.3390/ma15196849Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable AlloysViacheslav Bazhenov0Anna Li1Stanislav Tavolzhanskii2Andrey Bazlov3Natalia Tabachkova4Andrey Koltygin5Alexander Komissarov6Kwang Seon Shin7Casting Department, National University of Science and Technology “MISiS”, Leninskiy pr. 4, 119049 Moscow, RussiaLaboratory of Hybrid Nanostructured Materials, National University of Science and Technology “MISiS”, Leninskiy pr. 4, 119049 Moscow, RussiaCasting Department, National University of Science and Technology “MISiS”, Leninskiy pr. 4, 119049 Moscow, RussiaLaboratory of Advanced Green Materials, National University of Science and Technology “MISiS”, Leninskiy pr. 4, 119049 Moscow, RussiaDepartment of Materials Science of Semiconductors and Dielectrics, National University of Science and Technology “MISiS”, Leninskiy pr. 4, 119049 Moscow, RussiaCasting Department, National University of Science and Technology “MISiS”, Leninskiy pr. 4, 119049 Moscow, RussiaLaboratory of Hybrid Nanostructured Materials, National University of Science and Technology “MISiS”, Leninskiy pr. 4, 119049 Moscow, RussiaLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, Delegatskaya 20/1, 127473 Moscow, RussiaMagnesium alloys are attractive candidates for use as temporary fixation devices in osteosynthesis because they have a density and Young’s modulus similar to those of cortical bone. One of the main requirements for biodegradable implants is its substitution by tissues during the healing process. In this article, the Mg–Zn–Ga–(Y) alloys were investigated that potentially can increase the bone growth rate by release of Ga ions during the degradation process. Previously, the effectiveness of Ga ions on bone tissue regeneration has been proved by clinical tests. This work is the first systematic study on the microstructure and mechanical properties of Mg–Zn–Y alloys containing Ga as an additional major alloying element prepared by the hot-extrusion process. The microstructure and phase composition of the Mg–Zn–Ga–(Y) alloys in as-cast, heat-treated, and extruded conditions were analyzed. In addition, it was shown that the use of hot extrusion produces Mg–Zn–Ga–(Y) alloys with favorable mechanical properties. The tensile yield strength, ultimate tensile strength, and elongation at fracture of the MgZn4Ga4 alloy extruded at 150 °C were 256 MPa, 343 MPa, and 14.2%, respectively. Overall, MgZn4Ga4 alloy is a perspective for applications in implants for osteosynthesis with improved bone regeneration ability.https://www.mdpi.com/1996-1944/15/19/6849biomaterialsgalliumhot extrusionmagnesiummechanical propertiesmicrostructure
spellingShingle Viacheslav Bazhenov
Anna Li
Stanislav Tavolzhanskii
Andrey Bazlov
Natalia Tabachkova
Andrey Koltygin
Alexander Komissarov
Kwang Seon Shin
Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys
Materials
biomaterials
gallium
hot extrusion
magnesium
mechanical properties
microstructure
title Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys
title_full Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys
title_fullStr Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys
title_full_unstemmed Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys
title_short Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys
title_sort microstructure and mechanical properties of hot extruded mg zn ga y biodegradable alloys
topic biomaterials
gallium
hot extrusion
magnesium
mechanical properties
microstructure
url https://www.mdpi.com/1996-1944/15/19/6849
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