Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects

ABSTRACT Juvenile ossifying fibroma (JOF) is an uncommon benign fibro-osseous lesion that affects young individuals and deserves attention because it presents an aggressive clinical behavior and high rates of recurrence. This paper aims to report seven cases diagnosed as JOF - age ranging from 11 to...

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Main Authors: Katianne S. Rodrigues, Glória Maria França, Everton F. Morais, Joaquim Felipe Jr., Roseana A. Freitas, Hébel C. Galvão
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2020-03-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000600659&tlng=en
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author Katianne S. Rodrigues
Glória Maria França
Everton F. Morais
Joaquim Felipe Jr.
Roseana A. Freitas
Hébel C. Galvão
author_facet Katianne S. Rodrigues
Glória Maria França
Everton F. Morais
Joaquim Felipe Jr.
Roseana A. Freitas
Hébel C. Galvão
author_sort Katianne S. Rodrigues
collection DOAJ
description ABSTRACT Juvenile ossifying fibroma (JOF) is an uncommon benign fibro-osseous lesion that affects young individuals and deserves attention because it presents an aggressive clinical behavior and high rates of recurrence. This paper aims to report seven cases diagnosed as JOF - age ranging from 11 to 39 years - in a referral center, correlating our findings with clinical and pathological aspects in the literature. The mandible was the most common location, and in three cases, painful symptoms were reported. Regarding the histopathological findings, the majority of cases exhibited a cellularized pattern, and the trabecular subtype was the most commonly found. Regarding treatment, three cases relapsed, and, in two of them, conservative treatments were performed. Accordingly, knowing the clinical-pathological aspects of JOF is important for the correct diagnosis and the establishment of an appropriate treatment that decreases the high recurrence rate of this lesion.
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spelling doaj.art-5f4eb5d975c3457daf31158a6b84a80b2022-12-21T21:28:33ZengSociedade Brasileira de Patologia ClínicaJornal Brasileiro de Patologia e Medicina Laboratorial1678-47742020-03-0155665966810.5935/1676-2444.20190058Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspectsKatianne S. Rodrigueshttps://orcid.org/0000-0003-2413-2414Glória Maria FrançaEverton F. MoraisJoaquim Felipe Jr.Roseana A. FreitasHébel C. GalvãoABSTRACT Juvenile ossifying fibroma (JOF) is an uncommon benign fibro-osseous lesion that affects young individuals and deserves attention because it presents an aggressive clinical behavior and high rates of recurrence. This paper aims to report seven cases diagnosed as JOF - age ranging from 11 to 39 years - in a referral center, correlating our findings with clinical and pathological aspects in the literature. The mandible was the most common location, and in three cases, painful symptoms were reported. Regarding the histopathological findings, the majority of cases exhibited a cellularized pattern, and the trabecular subtype was the most commonly found. Regarding treatment, three cases relapsed, and, in two of them, conservative treatments were performed. Accordingly, knowing the clinical-pathological aspects of JOF is important for the correct diagnosis and the establishment of an appropriate treatment that decreases the high recurrence rate of this lesion.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000600659&tlng=enossifying fibromajaw neoplasmspathology
spellingShingle Katianne S. Rodrigues
Glória Maria França
Everton F. Morais
Joaquim Felipe Jr.
Roseana A. Freitas
Hébel C. Galvão
Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects
Jornal Brasileiro de Patologia e Medicina Laboratorial
ossifying fibroma
jaw neoplasms
pathology
title Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects
title_full Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects
title_fullStr Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects
title_full_unstemmed Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects
title_short Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects
title_sort juvenile ossifying fibroma series of seven cases focusing on clinical and pathological aspects
topic ossifying fibroma
jaw neoplasms
pathology
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000600659&tlng=en
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