The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer

The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer

Abstract Background Prevention of triple-negative breast cancer (TNBC) is hampered by lack of knowledge about the drivers of tumorigenesis. Methods To identify molecular markers and their downstream networks that can potentially be targeted for TNBC prevention, we analyzed small RNA and RNA sequenci...

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Bibliographic Details
Main Authors: Anjana Bhardwaj, Harpreet Singh, Celestine Marie Trinidad, Constance T. Albarracin, Kelly K. Hunt, Isabelle Bedrosian
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Breast Cancer Research
Subjects:
iso-miRNA
miR-140-3p-1
Statin
Aspirin
Dual targeting
AMPK activation
Online Access:http://link.springer.com/article/10.1186/s13058-018-1074-z

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