Challenges in Drug Discovery for Intracellular Bacteria
Novel drugs are needed to treat a variety of persistent diseases caused by intracellular bacterial pathogens. Virulence pathways enable many functions required for the survival of these pathogens, including invasion, nutrient acquisition, and immune evasion. Inhibition of virulence pathways is an es...
Main Authors: | Allison N. Tucker, Travis J. Carlson, Aurijit Sarkar |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
|
Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/10/9/1172 |
Similar Items
-
Discovery of in vivo Virulence Genes of Obligatory Intracellular Bacteria by Random Mutagenesis
by: Hannah Bekebrede, et al.
Published: (2020-02-01) -
Intracellular persister: A stealth agent recalcitrant to antibiotics
by: Nicolas Personnic, et al.
Published: (2023-03-01) -
Omics for Bioprospecting and Drug Discovery from Bacteria and Microalgae
by: Reuben Maghembe, et al.
Published: (2020-05-01) -
Editorial: Novel approaches to prevent and treat intracellular bacterial infections
by: Volker Behrends, et al.
Published: (2023-07-01) -
Immunity to intracellular bacteria
by: Stefan H. E. Kaufmann, et al.
Published: (1992-01-01)