Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension
Cell surface receptors are central to the cell's ability to generate coordinated responses to the multitude of biochemical and physical cues in the microenvironment. However, the mechanisms by which receptors enable this concerted cellular response remain unclear. To investigate the effect of c...
Main Authors: | Joanna P Rys, Christopher C DuFort, David A Monteiro, Michelle A Baird, Juan A Oses-Prieto, Shreya Chand, Alma L Burlingame, Michael W Davidson, Tamara N Alliston |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/09300 |
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