Design, Synthesis, In Vitro Biological Activity Evaluation and Stabilized Nanostructured Lipid Carrier Formulation of Newly Synthesized Schiff Bases-Based TMP Moieties

Design, Synthesis, In Vitro Biological Activity Evaluation and Stabilized Nanostructured Lipid Carrier Formulation of Newly Synthesized Schiff Bases-Based TMP Moieties

A series of novel Schiff bases-based TMP moieties have been designed and synthesized as potential anticancer agents. The target Schiff bases were screened for their cytotoxic activity against the MDA-MB-231 breast cancer cell line. Most of the tested molecules revealed good cytotoxic activity, espec...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Syed Nasir Abbas Bukhari, Mohamed Y. Zakaria, Muhammad Usman Munir, Naveed Ahmad, Mervat A Elsherif, Rasha Emad Badr, Ahmad Khalaf Hassan, Ali H. Abu Almaaty, Islam Zaki
Formatua:	Artikulua
Hizkuntza:	English
Argitaratua:	MDPI AG 2022-05-01
Saila:	Pharmaceuticals
Gaiak:	TMP Schiff base synthesis cytotoxicity tubulin cell cycle analysis
Sarrera elektronikoa:	https://www.mdpi.com/1424-8247/15/6/679

Antzeko izenburuak

Design, Synthesis and Cytotoxic Activity Evaluation of Newly Synthesized Amides-Based TMP Moiety as Potential Anticancer Agents over HepG2 Cells
nork: Tarfah Al-Warhi, et al.
Argitaratua: (2022-06-01)

Effects of Refiner Plates with Different Fillings on TMP Properties
nork: Hyeong-Hun Park, et al.
Argitaratua: (2023-04-01)

TMP-SMX induced type 4 hypersensitivity with multi-organ involvement
nork: Samantha Sircar, et al.
Argitaratua: (2023-01-01)

Synthesizing, Characterizing and Studying the Biological Activity of Some New Schiff-Bases Derivatives Containing the Monosaccharide Moiety
nork: Baghdad Science Journal
Argitaratua: (2016-09-01)

A COMPARISON BETWEEN THE EFFECTS OF OZONE AND ALKALINE PEROXIDE TREATMENTS ON TMP PROPERTIES AND SUBSEQUENT LOW CONSISTENCY REFINING
nork: James A. Olson, et al.
Argitaratua: (2011-11-01)

Construction and functional verification of size-reduced plasmids based on TMP resistance gene dfrB10
nork: Chun-cao Li, et al.
Argitaratua: (2023-12-01)

Tribological Performances of Trimethylolpropane (TMP) Blended with Graphene Oxide Using Four-Ball Tribotester
nork: Zulhanafi Paiman, et al.
Argitaratua: (2024-02-01)

Prophylactic antibiotic treatment with TMP-SMX decreased the incidence of interstitial pneumonia in patients with B-cell lymphoma on chemotherapy
nork: Cong Li, et al.
Argitaratua: (2020-08-01)

Synthesis and Biological Activity Screening of Newly Synthesized Trimethoxyphenyl-Based Analogues as Potential Anticancer Agents
nork: Tarfah Al-Warhi, et al.
Argitaratua: (2022-07-01)

TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro
nork: Juanbin Yin, et al.
Argitaratua: (2023-12-01)

NbTMP14 Is Involved in Tomato Spotted Wilt Virus Infection and Symptom Development by Interaction with the Viral NSm Protein
nork: Jin Zhan, et al.
Argitaratua: (2021-03-01)

Evaluation of Tribological Performance of Hydrogenated Dlc by Surface Texturing in the Presence of Palm Based Tmp Ester at Different Temperatures
nork: Mahendra Varman, et al.
Argitaratua: (2019-01-01)

Overexpression of a thylakoid membrane protein gene OsTMP14 improves indica rice cold tolerance
nork: Yongrong Liao, et al.
Argitaratua: (2017-07-01)

Synthesis and Spectroscopic Characterization of New Schiff Bases Containing the Benzo-15-Crown-5 Moiety
nork: Hakan Dal, et al.
Argitaratua: (2004-09-01)

Evaluating the diagnostic accuracy of TpN17 and TmpA recombinant proteins in syphilis detection: a phase II study
nork: Ângelo Antônio Oliveira Silva, et al.
Argitaratua: (2024-02-01)

Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis
nork: M. Beter, et al.
Argitaratua: (2025-01-01)

Exploration for the opioidergic, GABAergic and histaminergic potentials of synthesized Schiff’s base derivatives: An in-vivo approach
nork: Adnan Khan, et al.
Argitaratua: (2024-08-01)

Synthesis, characterization and biological studies on some metal complexes with Schiff base ligand containing pyrazolone moiety
nork: M. Sivasankaran Nair, et al.
Argitaratua: (2016-09-01)

Poly(vinyl Chloride) Photostabilization in the Presence of Schiff Bases Containing a Thiadiazole Moiety
nork: Naser Shaalan, et al.
Argitaratua: (2018-04-01)

Syntheses, Characterization, Antioxidant Activity, and Toxicity Evaluation of Schiff Base Derivates from O-Vanillin
nork: Ahmad Hanapi, et al.
Argitaratua: (2024-04-01)

Polymeric Copper(II) Complexes with a Newly Synthesized Biphenyldicarboxylic Acid Schiff Base Ligand—Synthesis, Structural and Thermal Characterization
nork: Milica G. Bogdanović, et al.
Argitaratua: (2022-12-01)

Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity
nork: Islam Zaki, et al.
Argitaratua: (2021-10-01)

The first reported pulmonary nocardiosis caused by Nocardia gipuzkoensis resisted to trimethoprim/sulfamethoxazol (TMP-SMZ) in an immunocompetent patient
nork: Yishan Duan, et al.
Argitaratua: (2024-06-01)

Synthesis and Characterization of Novel Schiff Bases of Imide Moiety
nork: Sulaiman M. Hasan, et al.
Argitaratua: (2017-04-01)

Azobenzene-Containing Schiff-Bases—Syntheses and Dyes Applications
nork: Estelle Leonard, et al.
Argitaratua: (2024-02-01)

Neuroprotective mechanism of TMP269, a selective class IIA histone deacetylase inhibitor, after cerebral ischemia/reperfusion injury
nork: Lu Su, et al.
Argitaratua: (2020-01-01)

Potentiometric and spectrophotometric studies of the complexation of Schiff-base hydrazones containing the pyrimidine moiety
nork: Seleem H.S., et al.
Argitaratua: (2003-01-01)

Synthesis and characterization of palladium(ii) and nickel(ii) schiff base complexes for homogenous catalytic and anticancer studies / Shahrul Nizam Ahmad
nork: Ahmad, Shahrul Nizam
Argitaratua: (2018)

Fabrication of copper-selective PVC membrane electrode based on newly synthesized copper complex of Schiff base as carrier
nork: Sulekh Chandra, et al.
Argitaratua: (2016-09-01)

Antileishmanial Activity of New Synthesized Schiff and Mannich (Morpholine) Base Compounds
nork: Şahin Direkel, et al.
Argitaratua: (2020-12-01)

Trimethoprim-sulfamethoxazole-induced Pancytopenia in a Newly Diagnosed HIV Patient
nork: Vikram B. Vikhe, et al.
Argitaratua: (2024-08-01)

Novel Schiff Bases Derived From Pyromellitic Dianhydride
nork: Athraa M. Saloom, et al.
Argitaratua: (2017-04-01)

PREVALENCE OF SYPHILIS AND HIV INFECTION IN BLOOD DONORS IN COSMOPOLITAN LAHORE DURING THE YEAR 2014
nork: Hamid Mahmood, et al.
Argitaratua: (2015-12-01)

The Effect of o-Substituents on Mass Spectra of Schiff Bases Synthesized from Salicylaldehyde
nork: Gökhan Denizli, et al.
Argitaratua: (2013-06-01)

Unravelling the adsorption and anti-corrosion potency of newly synthesized thiazole Schiff bases on C-steel in 1 M HCl: Computational and experimental implementations
nork: Ahmed A. Farag, et al.
Argitaratua: (2025-03-01)

Current Perspectives on Biological Screening of Newly Synthetised Sulfanilamide Schiff Bases as Promising Antibacterial and Antibiofilm Agents
nork: Maria Coanda, et al.
Argitaratua: (2024-03-01)

Syntheses and Structural Studies of Schiff Bases Involving Hydrogen Bonds
nork: JosÃƒÂ© Elguero, et al.
Argitaratua: (2006-06-01)

Interaction of Phenolic Schiff Bases Bearing Sulfhydryl Moieties with 2,2-Diphenyl-1-picrylhydrazyl Radical: Structure–Activity Relationship Study
nork: Iveta Turomsha, et al.
Argitaratua: (2023-11-01)

Anti-Proliferative Activity and Tubulin Targeting of Novel Micro and Nanoparticles Complexes of 4-Amino-3-Thion-1, 2, 4-Triazole Derivatives
nork: Atheer Ali, et al.
Argitaratua: (2020-03-01)

Synthesis and characterization of some new Schiff base azo disperse dyes based on chromene moiety for simultaneous dyeing and antimicrobial finishing
nork: Hagar Fathy, et al.
Argitaratua: (2024-10-01)