Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase

Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase

ABSTRACT Inositol pyrophosphate 1,5-IP8 regulates expression of a fission yeast phosphate homeostasis regulon, comprising phosphate acquisition genes pho1, pho84, and tgp1, via its action as an agonist of precocious termination of transcription of the upstream lncRNAs that repress PHO mRNA synthesis...

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Bibliographic Details
Main Authors: Shreya Ghosh, Ana M. Sanchez, Beate Schwer, Isabel Prucker, Nikolaus Jork, Henning J. Jessen, Stewart Shuman
Format: Article
Language:English
Published: American Society for Microbiology 2024-08-01
Series:mBio
Subjects:
inositol pyrophosphatase
inorganic polyphosphatase
Nudix hydrolase
phosphate homeostasis
Schizosaccharomyces pombe
Online Access:https://journals.asm.org/doi/10.1128/mbio.01084-24

Internet

https://journals.asm.org/doi/10.1128/mbio.01084-24

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