[18F]FE-PE2I DAT correlates with Parkinson’s disease duration, stage, and rigidity/bradykinesia scores: a PET radioligand validation study

[18F]FE-PE2I DAT correlates with Parkinson’s disease duration, stage, and rigidity/bradykinesia scores: a PET radioligand validation study

Abstract Background Correlations between dopamine transporter (DAT) availability and Parkinson’s disease (PD) motor symptoms vary depending on the imaging modality, choice of regions of interest and clinical measures. We aimed to validate the PET radioligand [18F]FE-PE2I as a clinical biomarker in P...

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Bibliographic Details
Main Authors: Vera S. Kerstens, Patrik Fazio, Mathias Sundgren, Christer Halldin, Per Svenningsson, Andrea Varrone
Format: Article
Language:English
Published: SpringerOpen 2023-04-01
Series:EJNMMI Research
Subjects:
[18F]FE-PE2I
DAT
Disease duration
Motor scores
Parkinson’s disease
Online Access:https://doi.org/10.1186/s13550-023-00974-7

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