The Impact of Selection at the Amino Acid Level on the Usage of Synonymous Codons

The Impact of Selection at the Amino Acid Level on the Usage of Synonymous Codons

There are two main forces that affect usage of synonymous codons: directional mutational pressure and selection. The effectiveness of protein translation is usually considered as the main selectional factor. However, biased codon usage can also be a byproduct of a general selection at the amino acid...

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Bibliographic Details
Main Authors: Paweł Błażej, Dorota Mackiewicz, Małgorzata Wnętrzak, Paweł Mackiewicz
Format: Article
Language:English
Published: Oxford University Press 2017-03-01
Series:G3: Genes, Genomes, Genetics
Subjects:
amino acid
codon usage
mutation
selection
synonymous codons
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.038125

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