Alendronate-functionalized double network hydrogel scaffolds for effective osteogenesis

Alendronate-functionalized double network hydrogel scaffolds for effective osteogenesis

Development of artificial bone substitutes mimicking the extracellular matrix is a promising strategy for bone repair and regeneration. In views of the actual requirement of biomechanics, biodegradability, and bioactivity, herein, a double-network (DN) hydrogel was constructed by interspersing a met...

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Bibliographic Details
Main Authors: Guoke Tang, Liang Zhu, Weiheng Wang, Dongqing Zuo, Changgui Shi, Xiaojie Yu, Rui Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Chemistry
Subjects:
GelMA
ALN
OSA
schiff base
DN hydrogel
osteogenic differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.977419/full

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