Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria.
<h4>Background</h4>HIV diagnosis is a watershed in women's childbearing experience. It is usually accompanied by the fear of death and stigmatisation. Women diagnosed of HIV are often sceptical about pregnancy. Meanwhile, availability of antiretroviral treatments has impacted positi...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0240247 |
| _version_ | 1818725008908746752 |
|---|---|
| author | Joshua Odunayo Akinyemi Rotimi Felix Afolabi Olutosin Alaba Awolude |
| author_facet | Joshua Odunayo Akinyemi Rotimi Felix Afolabi Olutosin Alaba Awolude |
| author_sort | Joshua Odunayo Akinyemi |
| collection | DOAJ |
| description | <h4>Background</h4>HIV diagnosis is a watershed in women's childbearing experience. It is usually accompanied by the fear of death and stigmatisation. Women diagnosed of HIV are often sceptical about pregnancy. Meanwhile, availability of antiretroviral treatments has impacted positively on childbearing experience among women living with HIV. We therefore investigated the timing of first childbirth after HIV diagnosis and its determinants among women in Ibadan, Nigeria.<h4>Methods</h4>We extracted and analysed data from a 2015 cross-sectional study on childbearing progression among 933 women living with HIV and receiving care at University College Hospital, Ibadan, Nigeria. Extended Cox proportional hazards regression, a semi-parametric event history model was used at 5% significance level.<h4>Results</h4>The women's mean age was 38.1 (± SD = 6.1) years and the median time to first birth after HIV diagnosis (FBI_HIV) was 8 years. The likelihood of first birth after HIV diagnosis was lower among women who desired more children (HR = 0.63, CI: 0.51-0.78). Women whose partners had primary and secondary education respectively were about 2.3 times more likely to shorten FBI_HIV compared to those whose partners had no formal education. Knowledge of partner's HIV-positive status (HR = 1.42, CI: 1.04,1.93) increased the likelihood of having a first birth after HIV diagnosis. Older age, longer duration on ART and a higher number of children at diagnosis were associated with a declined hazard of first birth after HIV diagnosis.<h4>Conclusions</h4>The median time to first childbirth after HIV diagnosis was long. Partner's HIV-positive status and higher educational attainment were associated with early childbearing after HIV diagnosis. |
| first_indexed | 2024-12-17T21:35:29Z |
| format | Article |
| id | doaj.art-5f6f690b57274b7fac24b456aa051d61 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-17T21:35:29Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-5f6f690b57274b7fac24b456aa051d612022-12-21T21:31:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011510e024024710.1371/journal.pone.0240247Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria.Joshua Odunayo AkinyemiRotimi Felix AfolabiOlutosin Alaba Awolude<h4>Background</h4>HIV diagnosis is a watershed in women's childbearing experience. It is usually accompanied by the fear of death and stigmatisation. Women diagnosed of HIV are often sceptical about pregnancy. Meanwhile, availability of antiretroviral treatments has impacted positively on childbearing experience among women living with HIV. We therefore investigated the timing of first childbirth after HIV diagnosis and its determinants among women in Ibadan, Nigeria.<h4>Methods</h4>We extracted and analysed data from a 2015 cross-sectional study on childbearing progression among 933 women living with HIV and receiving care at University College Hospital, Ibadan, Nigeria. Extended Cox proportional hazards regression, a semi-parametric event history model was used at 5% significance level.<h4>Results</h4>The women's mean age was 38.1 (± SD = 6.1) years and the median time to first birth after HIV diagnosis (FBI_HIV) was 8 years. The likelihood of first birth after HIV diagnosis was lower among women who desired more children (HR = 0.63, CI: 0.51-0.78). Women whose partners had primary and secondary education respectively were about 2.3 times more likely to shorten FBI_HIV compared to those whose partners had no formal education. Knowledge of partner's HIV-positive status (HR = 1.42, CI: 1.04,1.93) increased the likelihood of having a first birth after HIV diagnosis. Older age, longer duration on ART and a higher number of children at diagnosis were associated with a declined hazard of first birth after HIV diagnosis.<h4>Conclusions</h4>The median time to first childbirth after HIV diagnosis was long. Partner's HIV-positive status and higher educational attainment were associated with early childbearing after HIV diagnosis.https://doi.org/10.1371/journal.pone.0240247 |
| spellingShingle | Joshua Odunayo Akinyemi Rotimi Felix Afolabi Olutosin Alaba Awolude Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria. PLoS ONE |
| title | Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria. |
| title_full | Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria. |
| title_fullStr | Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria. |
| title_full_unstemmed | Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria. |
| title_short | Semi-parametric model for timing of first childbirth after HIV diagnosis among women of childbearing age in Ibadan, Nigeria. |
| title_sort | semi parametric model for timing of first childbirth after hiv diagnosis among women of childbearing age in ibadan nigeria |
| url | https://doi.org/10.1371/journal.pone.0240247 |
| work_keys_str_mv | AT joshuaodunayoakinyemi semiparametricmodelfortimingoffirstchildbirthafterhivdiagnosisamongwomenofchildbearingageinibadannigeria AT rotimifelixafolabi semiparametricmodelfortimingoffirstchildbirthafterhivdiagnosisamongwomenofchildbearingageinibadannigeria AT olutosinalabaawolude semiparametricmodelfortimingoffirstchildbirthafterhivdiagnosisamongwomenofchildbearingageinibadannigeria |