PRMT5 Promotes Cyclin E1 and Cell Cycle Progression in CD4 Th1 Cells and Correlates With EAE Severity

PRMT5 Promotes Cyclin E1 and Cell Cycle Progression in CD4 Th1 Cells and Correlates With EAE Severity

Multiple Sclerosis (MS) is a debilitating central nervous system disorder associated with inflammatory T cells. Activation and expansion of inflammatory T cells is thought to be behind MS relapses and influence disease severity. Protein arginine N-methyltransferase 5 (PRMT5) is a T cell activation-i...

Full description

Bibliographic Details
Main Authors: Stephanie A. Amici, Wissam Osman, Mireia Guerau-de-Arellano
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
PRMT5
cell cycle
relapsing-remitting experimental autoimmune encephalomyelitis
T cell
multiple sclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.695947/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.695947/full

Similar Items