Phagocytic Activities of Reactive Microglia and Astrocytes Associated with Prion Diseases Are Dysregulated in Opposite Directions

Phagocytic Activities of Reactive Microglia and Astrocytes Associated with Prion Diseases Are Dysregulated in Opposite Directions

Phagocytosis is one of the most important physiological functions of the glia directed at maintaining a healthy, homeostatic environment in the brain. Under a homeostatic environment, the phagocytic activities of astrocytes and microglia are tightly coordinated in time and space. In neurodegenerativ...

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Bibliographic Details
Main Authors: Anshuman Sinha, Rajesh Kushwaha, Kara Molesworth, Olga Mychko, Natallia Makarava, Ilia V. Baskakov
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
prions
prion diseases
neuroinflammation
reactive microglia
reactive astrocytes
phagocytosis
Online Access:https://www.mdpi.com/2073-4409/10/7/1728

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