The impact of gut microbiota on the development of refractory epilepsy
The gut microbiota could regulate brain function and behavior via microbiota⁃gut⁃brain axis and is associated with the pathogenesis of various neurological diseases. Significant alteration of gut microbiota is seen in patients with epilepsy, but consistent microbiota change has not yet been obtained...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2023-02-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/2627 |
| _version_ | 1811161427064389632 |
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| author | HONG Zhen |
| author_facet | HONG Zhen |
| author_sort | HONG Zhen |
| collection | DOAJ |
| description | The gut microbiota could regulate brain function and behavior via microbiota⁃gut⁃brain axis and is associated with the pathogenesis of various neurological diseases. Significant alteration of gut microbiota is seen in patients with epilepsy, but consistent microbiota change has not yet been obtained. We aimed to summarize the changes of gut microbiota in patients with epilepsy, the relationship between gut microbiota and epilepsy, the anti⁃seizure effect of gut microbiota, and the potential mechanism of gut microbiota⁃gut⁃brain axis in the pathogenesis of epilepsy, which would help to provide new therapeutic targets for the treatment of refractory epilepsy. |
| first_indexed | 2024-04-10T06:15:05Z |
| format | Article |
| id | doaj.art-5f77f5a6f78f4d9b960151a26a714642 |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-04-10T06:15:05Z |
| publishDate | 2023-02-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-5f77f5a6f78f4d9b960151a26a7146422023-03-02T09:38:18ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312023-02-012302697710.3969/j.issn.1672⁃6731.2023.02.001The impact of gut microbiota on the development of refractory epilepsyHONG Zhen0Department of Neurology, West China Hospital, Sichuan UniversityThe gut microbiota could regulate brain function and behavior via microbiota⁃gut⁃brain axis and is associated with the pathogenesis of various neurological diseases. Significant alteration of gut microbiota is seen in patients with epilepsy, but consistent microbiota change has not yet been obtained. We aimed to summarize the changes of gut microbiota in patients with epilepsy, the relationship between gut microbiota and epilepsy, the anti⁃seizure effect of gut microbiota, and the potential mechanism of gut microbiota⁃gut⁃brain axis in the pathogenesis of epilepsy, which would help to provide new therapeutic targets for the treatment of refractory epilepsy.http://www.cjcnn.org/index.php/cjcnn/article/view/2627epilepsygastrointestinal microbiomereview |
| spellingShingle | HONG Zhen The impact of gut microbiota on the development of refractory epilepsy Chinese Journal of Contemporary Neurology and Neurosurgery epilepsy gastrointestinal microbiome review |
| title | The impact of gut microbiota on the development of refractory epilepsy |
| title_full | The impact of gut microbiota on the development of refractory epilepsy |
| title_fullStr | The impact of gut microbiota on the development of refractory epilepsy |
| title_full_unstemmed | The impact of gut microbiota on the development of refractory epilepsy |
| title_short | The impact of gut microbiota on the development of refractory epilepsy |
| title_sort | impact of gut microbiota on the development of refractory epilepsy |
| topic | epilepsy gastrointestinal microbiome review |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/2627 |
| work_keys_str_mv | AT hongzhen theimpactofgutmicrobiotaonthedevelopmentofrefractoryepilepsy AT hongzhen impactofgutmicrobiotaonthedevelopmentofrefractoryepilepsy |