Licorice as a herbal extract in periodontal therapy
Periodontal disease is caused by specific pathogens which results in inflammation of the tooth-supporting structures and subsequently causes the continued breakdown of alveolar bone and periodontal ligament. Licorice (Glycyrrhiza glabra) is a perennial herb with substantial medicinal value. Licorice...
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| Format: | Article |
| Language: | English |
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AboutScience Srl
2023-06-01
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| Series: | Drug Target Insights |
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| Online Access: | https://journals.aboutscience.eu/index.php/dti/article/view/2583 |
| _version_ | 1797810779908472832 |
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| author | Safiya Fatima Khan Bhavya Shetty Ibrahim Fazal Asim Mustafa Khan Faheem Muzaffar Mir Muhamood Moothedath Reshma VJ Muhaseena Muhamood |
| author_facet | Safiya Fatima Khan Bhavya Shetty Ibrahim Fazal Asim Mustafa Khan Faheem Muzaffar Mir Muhamood Moothedath Reshma VJ Muhaseena Muhamood |
| author_sort | Safiya Fatima Khan |
| collection | DOAJ |
| description | Periodontal disease is caused by specific pathogens which results in inflammation of the tooth-supporting structures and subsequently causes the continued breakdown of alveolar bone and periodontal ligament. Licorice (Glycyrrhiza glabra) is a perennial herb with substantial medicinal value. Licorice extract is derived from dried, unpeeled stolons and roots of Glycyrrhiza uralensis and G. glabra. The bioactive ingredients in licorice extract such as glycyrrhizin, licoricidin, glabridin, licochalcone A, and licorisoflavan A have anti-inflammatory, antimicrobial, and anti-adherence effects that are beneficial against periodontal disease. Since periodontal disease has a complex etiology that includes the host response and microorganisms, licorice phytochemicals offer a therapeutic advantage due to their dual functionality. The aim of this review was to enumerate the bioactive compounds present in herbal licorice extract and to elucidate the beneficial effects of licorice and its derivatives in periodontal therapy. Literature review and clinical trials evaluating the effect of licorice on periodontopathogens and periodontal disease are included in this article.
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| first_indexed | 2024-03-13T07:13:54Z |
| format | Article |
| id | doaj.art-5f78ad094733466cb7ecdd62f3ba1b7b |
| institution | Directory Open Access Journal |
| issn | 1177-3928 |
| language | English |
| last_indexed | 2024-03-13T07:13:54Z |
| publishDate | 2023-06-01 |
| publisher | AboutScience Srl |
| record_format | Article |
| series | Drug Target Insights |
| spelling | doaj.art-5f78ad094733466cb7ecdd62f3ba1b7b2023-06-05T12:20:37ZengAboutScience SrlDrug Target Insights1177-39282023-06-0117110.33393/dti.2023.2583Licorice as a herbal extract in periodontal therapySafiya Fatima Khan0Bhavya Shetty1Ibrahim Fazal2Asim Mustafa Khan3Faheem Muzaffar Mir4Muhamood Moothedath5Reshma VJ6Muhaseena Muhamood7Department of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bangalore - IndiaDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bangalore - IndiaDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bangalore - IndiaDepartment of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam - Saudi ArabiaDepartment of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam - Saudi ArabiaDepartment of Oral and Dental Health, College of Applied Health Sciences in Arrass, Qassim University, Buraidah - Saudi ArabiaDepartment of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam - Saudi ArabiaDepartment of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam - Saudi ArabiaPeriodontal disease is caused by specific pathogens which results in inflammation of the tooth-supporting structures and subsequently causes the continued breakdown of alveolar bone and periodontal ligament. Licorice (Glycyrrhiza glabra) is a perennial herb with substantial medicinal value. Licorice extract is derived from dried, unpeeled stolons and roots of Glycyrrhiza uralensis and G. glabra. The bioactive ingredients in licorice extract such as glycyrrhizin, licoricidin, glabridin, licochalcone A, and licorisoflavan A have anti-inflammatory, antimicrobial, and anti-adherence effects that are beneficial against periodontal disease. Since periodontal disease has a complex etiology that includes the host response and microorganisms, licorice phytochemicals offer a therapeutic advantage due to their dual functionality. The aim of this review was to enumerate the bioactive compounds present in herbal licorice extract and to elucidate the beneficial effects of licorice and its derivatives in periodontal therapy. Literature review and clinical trials evaluating the effect of licorice on periodontopathogens and periodontal disease are included in this article. https://journals.aboutscience.eu/index.php/dti/article/view/2583GingivitisGlycyrrhiza glabraHerbal therapyPeriodontitis |
| spellingShingle | Safiya Fatima Khan Bhavya Shetty Ibrahim Fazal Asim Mustafa Khan Faheem Muzaffar Mir Muhamood Moothedath Reshma VJ Muhaseena Muhamood Licorice as a herbal extract in periodontal therapy Drug Target Insights Gingivitis Glycyrrhiza glabra Herbal therapy Periodontitis |
| title | Licorice as a herbal extract in periodontal therapy |
| title_full | Licorice as a herbal extract in periodontal therapy |
| title_fullStr | Licorice as a herbal extract in periodontal therapy |
| title_full_unstemmed | Licorice as a herbal extract in periodontal therapy |
| title_short | Licorice as a herbal extract in periodontal therapy |
| title_sort | licorice as a herbal extract in periodontal therapy |
| topic | Gingivitis Glycyrrhiza glabra Herbal therapy Periodontitis |
| url | https://journals.aboutscience.eu/index.php/dti/article/view/2583 |
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