Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel concept
Abstract Background Benign joint hypermobility syndrome (BJHS) is one of the most common hereditary connective tissue disorders in children in which autonomic nervous system involvement has been reported. This study aimed to evaluate the frequency of primary focal hyperhidrosis in children with BJHS...
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| Format: | Article |
| Language: | English |
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BMC
2020-04-01
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| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12891-020-03264-8 |
| _version_ | 1819003306600562688 |
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| author | Vadood Javadi Parvaneh Hoda Shahvaladi Khosro Rahmani Sara Javdani Yekta Fatemeh Abdollah Gorji Reza Shiari Fahimeh Abdollahimajd |
| author_facet | Vadood Javadi Parvaneh Hoda Shahvaladi Khosro Rahmani Sara Javdani Yekta Fatemeh Abdollah Gorji Reza Shiari Fahimeh Abdollahimajd |
| author_sort | Vadood Javadi Parvaneh |
| collection | DOAJ |
| description | Abstract Background Benign joint hypermobility syndrome (BJHS) is one of the most common hereditary connective tissue disorders in children in which autonomic nervous system involvement has been reported. This study aimed to evaluate the frequency of primary focal hyperhidrosis in children with BJHS. Methods This observational-analytical study was conducted in a case-control setting on children aged 3 to 15 years in 2018 at Mofid Children’s Hospital, Tehran, Iran. Benign joint hypermobility syndrome was diagnosed according to the Brighton criteria; then, the patients referred to a dermatologist for evaluation of hyperhidrosis. Results In total, 130 eligible patients with confirmed BJHS and 160 age- and sex-matched healthy subjects were enrolled in this study. Primary focal hyperhidrosis (PFH) was seen in 56.2 and 16.3% of the cases and controls, respectively, indicating a significant difference (P < 0.05). The severity of hyperhidrosis did not differ between the two groups. Conclusion Although the results of the study showed a significant correlation between BJHS and PFH, more comprehensive studies are needed to confirm these findings. |
| first_indexed | 2024-12-20T23:18:54Z |
| format | Article |
| id | doaj.art-5f7dffd36dcd4adb96bbc700a96f6891 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-20T23:18:54Z |
| publishDate | 2020-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-5f7dffd36dcd4adb96bbc700a96f68912022-12-21T19:23:35ZengBMCBMC Musculoskeletal Disorders1471-24742020-04-012111510.1186/s12891-020-03264-8Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel conceptVadood Javadi Parvaneh0Hoda Shahvaladi1Khosro Rahmani2Sara Javdani Yekta3Fatemeh Abdollah Gorji4Reza Shiari5Fahimeh Abdollahimajd6Pediatric Pathology Research Center, Shahid Beheshti University of Medical SciencesPediatric Pathology Research Center, Shahid Beheshti University of Medical SciencesDepartment of Pediatric Rheumatology, Shahid Beheshti University of Medical SciencesDepartment of Pediatric Rheumatology, Shahid Beheshti University of Medical SciencesPediatric Pathology Research Center, Shahid Beheshti University of Medical SciencesDepartment of Pediatric Rheumatology, Shahid Beheshti University of Medical SciencesSkin Research Center, Shahid Beheshti University of Medical SciencesAbstract Background Benign joint hypermobility syndrome (BJHS) is one of the most common hereditary connective tissue disorders in children in which autonomic nervous system involvement has been reported. This study aimed to evaluate the frequency of primary focal hyperhidrosis in children with BJHS. Methods This observational-analytical study was conducted in a case-control setting on children aged 3 to 15 years in 2018 at Mofid Children’s Hospital, Tehran, Iran. Benign joint hypermobility syndrome was diagnosed according to the Brighton criteria; then, the patients referred to a dermatologist for evaluation of hyperhidrosis. Results In total, 130 eligible patients with confirmed BJHS and 160 age- and sex-matched healthy subjects were enrolled in this study. Primary focal hyperhidrosis (PFH) was seen in 56.2 and 16.3% of the cases and controls, respectively, indicating a significant difference (P < 0.05). The severity of hyperhidrosis did not differ between the two groups. Conclusion Although the results of the study showed a significant correlation between BJHS and PFH, more comprehensive studies are needed to confirm these findings.http://link.springer.com/article/10.1186/s12891-020-03264-8Benign joint hypermobility syndrome (BJHS)Primary focal hyperhidrosisPediatrics/childrenPalmoplantar hyperhidrosisAxillary hyperhidrosis |
| spellingShingle | Vadood Javadi Parvaneh Hoda Shahvaladi Khosro Rahmani Sara Javdani Yekta Fatemeh Abdollah Gorji Reza Shiari Fahimeh Abdollahimajd Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel concept BMC Musculoskeletal Disorders Benign joint hypermobility syndrome (BJHS) Primary focal hyperhidrosis Pediatrics/children Palmoplantar hyperhidrosis Axillary hyperhidrosis |
| title | Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel concept |
| title_full | Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel concept |
| title_fullStr | Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel concept |
| title_full_unstemmed | Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel concept |
| title_short | Correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children: a novel concept |
| title_sort | correlation between benign joint hypermobility syndrome and primary focal hyperhidrosis in children a novel concept |
| topic | Benign joint hypermobility syndrome (BJHS) Primary focal hyperhidrosis Pediatrics/children Palmoplantar hyperhidrosis Axillary hyperhidrosis |
| url | http://link.springer.com/article/10.1186/s12891-020-03264-8 |
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