Molecular Mechanisms to Target Cellular Senescence in Hepatocellular Carcinoma

Molecular Mechanisms to Target Cellular Senescence in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death and is the most common type of liver cancer. Due to the current paucity of drugs for HCC therapy there is a pressing need to develop new therapeutic concepts. In recent years, the role of Serum Response Factor (SRF)...

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Bibliographic Details
Main Authors: Constanze Mittermeier, Andreas Konopa, Susanne Muehlich
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
senescence
HCC
SRF
DLC1
MRTF
senolytics
Online Access:https://www.mdpi.com/2073-4409/9/12/2540

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