Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei
Microplastics (MPs) pose one of the major environmental threats to marine organisms and ecosystems on a global scale. Although many marine crustaceans are highly susceptible to MPs pollution, the toxicological effects and mechanisms of MPs on crustaceans are poorly understood. The current study focu...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-05-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651323003755 |
| _version_ | 1827960886900293632 |
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| author | Yingxu Zeng Baichuan Deng Zixin Kang Pedro Araujo Svein Are Mjøs Ruina Liu Jianhui Lin Tao Yang Yuangao Qu |
| author_facet | Yingxu Zeng Baichuan Deng Zixin Kang Pedro Araujo Svein Are Mjøs Ruina Liu Jianhui Lin Tao Yang Yuangao Qu |
| author_sort | Yingxu Zeng |
| collection | DOAJ |
| description | Microplastics (MPs) pose one of the major environmental threats to marine organisms and ecosystems on a global scale. Although many marine crustaceans are highly susceptible to MPs pollution, the toxicological effects and mechanisms of MPs on crustaceans are poorly understood. The current study focused on the impacts of MPs accumulation in shrimp Litopenaeus vannamei at the behavioral, histological and biochemical levels. The results demonstrated the accumulation of polystyrene MPs in various organs of L. vannamei, with highest MPs abundance in the hepatopancreas. The MPs accumulated in shrimp caused growth inhibition, abnormal swimming behavior and reduced swimming performance of L. vannamei. Following MPs exposure, oxidative stress and lipid peroxidation were also observed, which were strongly linked to attenuated swimming activity of L. vannamei. The above MPs-induced disruption in balance of antioxidant system triggered the hepatopancreatic damage in L. vannamei, which was exacerbated with increasing MPs concentrations (from 0.02 to 1 mg L−1). Furthermore, metabolomics revealed that MPs exposure resulted in alterations of metabolic profiles and disturbed glycolysis, lipolysis and amino acid metabolism pathways in hepatopancreas of L. vannamei. This work confirms and expands the knowledge on the sublethal impacts and toxic modes of action of MPs in L. vannamei. |
| first_indexed | 2024-04-09T16:16:58Z |
| format | Article |
| id | doaj.art-5f873576ecdd4862863bd8a09031065e |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-04-09T16:16:58Z |
| publishDate | 2023-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-5f873576ecdd4862863bd8a09031065e2023-04-24T04:37:21ZengElsevierEcotoxicology and Environmental Safety0147-65132023-05-01256114871Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannameiYingxu Zeng0Baichuan Deng1Zixin Kang2Pedro Araujo3Svein Are Mjøs4Ruina Liu5Jianhui Lin6Tao Yang7Yuangao Qu8Key Laboratory for Coastal Marine Eco-Environment Process and Carbon Sink of Hainan Province, Yazhou Bay Innovation Institute, College of Ecology and Environment, Hainan Tropical Ocean University, Sanya 572000, China; Correspondence to: Hainan Tropical Ocean University, No. 1 Yucai Road, Sanya 572000, China.Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, ChinaKey Laboratory for Coastal Marine Eco-Environment Process and Carbon Sink of Hainan Province, Yazhou Bay Innovation Institute, College of Ecology and Environment, Hainan Tropical Ocean University, Sanya 572000, ChinaInstitute of Marine Research, 5817 Bergen, NorwayDepartment of Chemistry, University of Bergen, N-5020 Bergen, NorwayKey Laboratory for Coastal Marine Eco-Environment Process and Carbon Sink of Hainan Province, Yazhou Bay Innovation Institute, College of Ecology and Environment, Hainan Tropical Ocean University, Sanya 572000, ChinaKey Laboratory for Coastal Marine Eco-Environment Process and Carbon Sink of Hainan Province, Yazhou Bay Innovation Institute, College of Ecology and Environment, Hainan Tropical Ocean University, Sanya 572000, ChinaKey Laboratory for Coastal Marine Eco-Environment Process and Carbon Sink of Hainan Province, Yazhou Bay Innovation Institute, College of Ecology and Environment, Hainan Tropical Ocean University, Sanya 572000, ChinaInstitute of Deep-Sea Science and Engineering, Chinese Academy of Sciences, Sanya 572000, ChinaMicroplastics (MPs) pose one of the major environmental threats to marine organisms and ecosystems on a global scale. Although many marine crustaceans are highly susceptible to MPs pollution, the toxicological effects and mechanisms of MPs on crustaceans are poorly understood. The current study focused on the impacts of MPs accumulation in shrimp Litopenaeus vannamei at the behavioral, histological and biochemical levels. The results demonstrated the accumulation of polystyrene MPs in various organs of L. vannamei, with highest MPs abundance in the hepatopancreas. The MPs accumulated in shrimp caused growth inhibition, abnormal swimming behavior and reduced swimming performance of L. vannamei. Following MPs exposure, oxidative stress and lipid peroxidation were also observed, which were strongly linked to attenuated swimming activity of L. vannamei. The above MPs-induced disruption in balance of antioxidant system triggered the hepatopancreatic damage in L. vannamei, which was exacerbated with increasing MPs concentrations (from 0.02 to 1 mg L−1). Furthermore, metabolomics revealed that MPs exposure resulted in alterations of metabolic profiles and disturbed glycolysis, lipolysis and amino acid metabolism pathways in hepatopancreas of L. vannamei. This work confirms and expands the knowledge on the sublethal impacts and toxic modes of action of MPs in L. vannamei.http://www.sciencedirect.com/science/article/pii/S0147651323003755ShrimpToxicityBiomarkersMetabolomicsCrustaceans |
| spellingShingle | Yingxu Zeng Baichuan Deng Zixin Kang Pedro Araujo Svein Are Mjøs Ruina Liu Jianhui Lin Tao Yang Yuangao Qu Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei Ecotoxicology and Environmental Safety Shrimp Toxicity Biomarkers Metabolomics Crustaceans |
| title | Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei |
| title_full | Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei |
| title_fullStr | Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei |
| title_full_unstemmed | Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei |
| title_short | Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei |
| title_sort | tissue accumulation of polystyrene microplastics causes oxidative stress hepatopancreatic injury and metabolome alterations in litopenaeus vannamei |
| topic | Shrimp Toxicity Biomarkers Metabolomics Crustaceans |
| url | http://www.sciencedirect.com/science/article/pii/S0147651323003755 |
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