Non-structural protein NS3/NS3a is required for propagation of bluetongue virus in Culicoides sonorensis

Non-structural protein NS3/NS3a is required for propagation of bluetongue virus in Culicoides sonorensis

Abstract Background Bluetongue virus (BTV) causes non-contagious haemorrhagic disease in ruminants and is transmitted by Culicoides spp. biting midges. BTV encodes four non-structural proteins of which NS3/NS3a is functional in virus release. NS3/NS3a is not essential for in vitro virus replication....

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Bibliographic Details
Main Authors: Femke Feenstra, Barbara S. Drolet, Jan Boonstra, Piet A. van Rijn
Format: Article
Language:English
Published: BMC 2015-09-01
Series:Parasites & Vectors
Subjects:
Bluetongue virus
Culicoides
Arbovirus
DISA vaccine
NS3/NS3a
Midge
Online Access:https://doi.org/10.1186/s13071-015-1063-3

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